MedPath

Dexmedetomidine

Generic Name
Dexmedetomidine
Brand Names
Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
Drug Type
Small Molecule
Chemical Formula
C13H16N2
CAS Number
113775-47-6
Unique Ingredient Identifier
67VB76HONO
Background

An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.

Indication

Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.

Associated Conditions
Agitation, Alcohol Withdrawal Syndrome
Associated Therapies
-
Clinical Trials
Related News

The Effects of Dexmedetomidine on Microcirculation and Surgical Outcomes After Cardiac Surgeries

Not Applicable
Completed
Conditions
Cardiac Surgical Procedure
Interventions
Drug: Dexmedetomidine
Drug: Normal Saline
First Posted Date
2016-05-30
Last Posted Date
2024-05-06
Lead Sponsor
National Taiwan University Hospital
Target Recruit Count
70
Registration Number
NCT02786212
Locations
🇨🇳

National Taiwan University Hospital, Taipei, Taiwan

Intraoperative Sedatives and Postoperative Pain

Phase 4
Completed
Conditions
Arthritis, Degenerative
Interventions
Drug: Dexmedetomidine
Drug: Propofol
First Posted Date
2016-05-27
Last Posted Date
2016-10-27
Lead Sponsor
Seoul National University Bundang Hospital
Target Recruit Count
48
Registration Number
NCT02784626
Locations
🇰🇷

Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea, Republic of

Dexmedetomidine Verses Propofol for Paediatric MRI Brain

Phase 4
Completed
Conditions
Brain Diseases
Interventions
Drug: Dexmedetomidine
Drug: propofol
Drug: Midazolam
First Posted Date
2016-05-18
Last Posted Date
2016-07-19
Lead Sponsor
Maharashtra University of Health Sciences
Target Recruit Count
70
Registration Number
NCT02776189
Locations
🇮🇳

Lokmanya Tilak Municipal General Hospital and Lokmanya Tilak Municipal Medical College, Mumbai, Maharastra, India

MRI of Glymphatic Clearance During Anesthetic Sedation

Early Phase 1
Completed
Conditions
Glymphatic Flow
Interventions
Other: Brain connectivity and physiology
Drug: Dexmedetomidine
First Posted Date
2016-05-11
Last Posted Date
2018-01-25
Lead Sponsor
University of Pennsylvania
Target Recruit Count
17
Registration Number
NCT02768688
Locations
🇺🇸

University of Pennsylvania, Philadelphia, Pennsylvania, United States

Use of Preanesthetic Dexmedetomidine in Elderly, Treated-hypertensive Patients

Phase 4
Completed
Conditions
Perioperative Care
Interventions
Drug: Normal Saline
Drug: Dexmedetomidine
First Posted Date
2016-05-11
Last Posted Date
2016-05-11
Lead Sponsor
DongGuk University
Target Recruit Count
2
Registration Number
NCT02768610

The Effect of Dexamedetomidine for Interscalene Brachial Plexus Block on Plasma Biomarkers After Rotator Cuff Repair

Not Applicable
Completed
Conditions
Pain
Interventions
Drug: dexmedetomidine
Drug: Ropivacaine
Procedure: ISB
First Posted Date
2016-05-10
Last Posted Date
2016-05-10
Lead Sponsor
Chuncheon Sacred Heart Hospital
Target Recruit Count
50
Registration Number
NCT02766556

Can Caudal Dexmedetomidine Prevents Sevoflurane Induced Emergence Agitation in Children

Phase 4
Completed
Conditions
Delayed Emergence From Anesthesia
Interventions
Drug: Dexmedetomidine
First Posted Date
2016-05-02
Last Posted Date
2019-02-27
Lead Sponsor
Suez Canal University
Target Recruit Count
48
Registration Number
NCT02757495
Locations
🇪🇬

Suez canal University hospital, Ismailia, Egypt

Dexmedetomidine on Optic Nerve Sheath Diameter

Not Applicable
Withdrawn
Conditions
Intracranial Hypertension
Interventions
Drug: normal saline
Drug: Dexmedetomidine
First Posted Date
2016-04-27
Last Posted Date
2016-11-10
Lead Sponsor
Gachon University Gil Medical Center
Registration Number
NCT02753205

A Multicenter Study: Dexmedetomidine Combined With Sufentanil for Patient Controlled Intravenous Analgesia After Caesarean Section

Phase 4
Completed
Conditions
Postoperative Pain
Interventions
Drug: Normal saline
Drug: Dexmedetomidine
Drug: Sufentanil
Drug: Sufentanil and dexmedetomidine
First Posted Date
2016-04-18
Last Posted Date
2021-05-07
Lead Sponsor
Obstetrics & Gynecology Hospital of Fudan University
Target Recruit Count
225
Registration Number
NCT02741219
Locations
🇨🇳

Obstetrics & Gynecology Hospital of Fudan University, Shanghai, Shanghai, China

Multimodal Analgesia in Cardiac Surgery (Pilot Study)

Phase 4
Terminated
Conditions
Heart Diseases
Interventions
Drug: Unrestricted Fentanyl
Drug: Lidocaine
Drug: Ketamine
Drug: Precedex
Drug: Duramorph
First Posted Date
2016-04-12
Last Posted Date
2018-08-07
Lead Sponsor
Virginia Commonwealth University
Target Recruit Count
3
Registration Number
NCT02734940
Locations
🇺🇸

Virginia Commonwealth University, Richmond, Virginia, United States

© Copyright 2025. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy