Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
Determine the ED50 of Dexmedetomidine to Facilitate LMA Insertion During Anaesthesia Induction
- First Posted Date
- 2015-03-12
- Last Posted Date
- 2015-03-12
- Target Recruit Count
- 30
- Registration Number
- NCT02386462
- Locations
- 🇨🇳
Guangzhou Military Region General Hospital, Department of Anesthesiology, Guangzhou, Guangdong, China
Intravenous Dexmedetomidine for Treatment of Shivering During Cesarean Section Under Neuraxial Anesthesia
- First Posted Date
- 2015-03-10
- Last Posted Date
- 2018-04-19
- Lead Sponsor
- St. Justine's Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT02384343
- Locations
- 🇨🇦
St-Justine's Hospital, Montréal, Quebec, Canada
Dexmedetomidine in Post Spinal Anesthesia Shivering
- Conditions
- Interventions
- First Posted Date
- 2015-03-06
- Last Posted Date
- 2015-03-06
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 120
- Registration Number
- NCT02382432
- Locations
- 🇪🇬
Assiut university hospital, Assiut, Egypt, Assiut, Assiut governorate, Egypt
A Comparative Study of the Effect of Epidural Dexmedetomidine Versus Fentanyl Added to Ropivacaine in Pediatric Orthopedic Surgery
- Conditions
- Interventions
- First Posted Date
- 2015-03-02
- Last Posted Date
- 2016-08-17
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 58
- Registration Number
- NCT02375191
- Locations
- 🇰🇷
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea, Republic of
Use of Dexmedetomidine in Children Undergoing Cardiac Surgery
- First Posted Date
- 2015-03-02
- Last Posted Date
- 2017-02-14
- Lead Sponsor
- Bambino Gesù Hospital and Research Institute
- Target Recruit Count
- 60
- Registration Number
- NCT02375243
- Locations
- 🇮🇹
Bambino Gesù Children's Hospital, Rome, Italy
Comparison of Dexmedetomidine and Propofol on the Delirium and Neuroinflammation in Patients With SIRS.
Can we Get Conscious Sedation by Combining Dexmedetomidine With Alfentanil?
- First Posted Date
- 2015-02-06
- Last Posted Date
- 2016-07-06
- Target Recruit Count
- 40
- Registration Number
- NCT02358057
A Pilot Study to Assess the Amnesic Properties of Dexmedetomidine in Pediatric Patients
- First Posted Date
- 2015-02-03
- Last Posted Date
- 2019-02-28
- Lead Sponsor
- Boston Children's Hospital
- Target Recruit Count
- 84
- Registration Number
- NCT02354378
- Locations
- 🇺🇸
Boston Children's Hospital, Boston, Massachusetts, United States
The T REX Pilot Study: a Study to Investigate the Use of an Alternative Anaesthetic in Infants.
- Conditions
- Interventions
- First Posted Date
- 2015-02-02
- Last Posted Date
- 2016-10-26
- Lead Sponsor
- Murdoch Childrens Research Institute
- Target Recruit Count
- 60
- Registration Number
- NCT02353182
- Locations
- 🇺🇸
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States
🇺🇸Texas Children's Hospital, Houston, Texas, United States
🇸🇬KK Women's and Children's Hospital, Singapore, Singapore
The Effects of Dexmedetomidine on the Heart Beat During Elective Surgery in Children
- Conditions
- Interventions
- First Posted Date
- 2015-02-02
- Last Posted Date
- 2019-10-07
- Lead Sponsor
- University of British Columbia
- Target Recruit Count
- 64
- Registration Number
- NCT02353169
- Locations
- 🇨🇦
BC Children's Hospital - Department of Anesthesia, Vancouver, British Columbia, Canada
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.