MedPath

Alfentanil

Generic Name
Alfentanil
Brand Names
Alfenta
Drug Type
Small Molecule
Chemical Formula
C21H32N6O3
CAS Number
71195-58-9
Unique Ingredient Identifier
1N74HM2BS7
Background

A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.

Indication

For the management of postoperative pain and the maintenance of general anesthesia.

Associated Therapies
General Anesthesia, Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Perioperative analgesia
Clinical Trials
Related News

To Explore the Optimal Dose of Alfentanil for Skull Pin Fixation in Intracranial Surgery

Phase 4
Not yet recruiting
Conditions
Procedural Pain
Interventions
First Posted Date
2024-08-20
Last Posted Date
2024-08-20
Lead Sponsor
Kaohsiung Medical University Chung-Ho Memorial Hospital
Target Recruit Count
40
Registration Number
NCT06563297
Locations
🇨🇳

Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan

Effect of Equivalent Dose of Alfentanil and Sufentanil in Bronchoscopic Treatment

Not Applicable
Completed
Conditions
Effect of Drug
Interventions
First Posted Date
2024-05-14
Last Posted Date
2025-01-14
Lead Sponsor
Tongji Hospital
Target Recruit Count
80
Registration Number
NCT06414018
Locations
🇨🇳

Aijun Xu, Hubei, Wuhan, China

Is the Rate of Early Mobilisation in Hip Fracture Patients Using Alfentanil Better Than Standard Opioid Analgesia?

Completed
Conditions
Early Ambulation
Hip Fractures
Hip Injuries
Pain
Post Operative Pain
Interventions
First Posted Date
2024-01-19
Last Posted Date
2024-12-06
Lead Sponsor
NHS Lothian
Target Recruit Count
64
Registration Number
NCT06212622
Locations
🇬🇧

Royal Infirmary of Edinburgh, Edinburgh, Lothian, United Kingdom

The Application and Validation of Triple Drug Response Surface Models on Density Spectral Array in Clinical Anesthesia

Not yet recruiting
Conditions
Drug Interaction
Anesthesia; Functional
Anesthesia
Interventions
Device: Bispectral index (BIS) or Patient State Index (PSI)
First Posted Date
2022-09-01
Last Posted Date
2022-09-07
Lead Sponsor
Taipei Veterans General Hospital, Taiwan
Target Recruit Count
60
Registration Number
NCT05525351
Locations
🇨🇳

Taipei Veterans General Hospital, Taipei, Taiwan

Use of Intrathecal Analgesia in Appendectomy

Not Applicable
Completed
Conditions
Anesthesia
Analgesia
Interventions
First Posted Date
2019-12-12
Last Posted Date
2019-12-12
Lead Sponsor
Nigde Omer Halisdemir University
Target Recruit Count
50
Registration Number
NCT04196946

Modeling and Application of Triple Drug Response Surface Models

Completed
Conditions
Drug Interactions
Pharmacodynamics
Interventions
Other: Bispectral index (BIS) and analgesia nociception index (ANI)
First Posted Date
2019-01-23
Last Posted Date
2022-07-20
Lead Sponsor
Taipei Veterans General Hospital, Taiwan
Target Recruit Count
100
Registration Number
NCT03813875
Locations
🇨🇳

Taipei Veterans General Hospital, Taipei, Taiwan

Pre-medication With Alfentanil vs Placebo During ECT

Phase 4
Completed
Conditions
Blood Pressure
Electroconvulsive Therapy
Interventions
Drug: Placebos
First Posted Date
2017-12-02
Last Posted Date
2021-07-08
Lead Sponsor
Wake Forest University Health Sciences
Target Recruit Count
100
Registration Number
NCT03359395
Locations
🇺🇸

Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States

Effect of a Bolus of 10 µg/kg of Alfentanil on the Pupillary Pain Index

Not Applicable
Completed
Conditions
Pain
Anesthesia
Interventions
First Posted Date
2016-01-05
Last Posted Date
2017-05-03
Lead Sponsor
Pr Isabelle CONSTANT
Target Recruit Count
14
Registration Number
NCT02646592
Locations
🇫🇷

Departement d'anesthesie Hopital Armand Trousseau, Paris, France

Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis

Not Applicable
Completed
Conditions
Postoperative Nausea and Vomiting
Interventions
Procedure: Automated recommendation at the start of the case
Procedure: Automated notification at the start of surgery
Procedure: Automated notification at the end of surgery
Device: Anesthesia Information Management System (AIMS)
Device: Perioperative Data Warehouse (PDW)
Procedure: General anesthesia
Procedure: Elective surgery
First Posted Date
2015-12-09
Last Posted Date
2019-03-07
Lead Sponsor
Vanderbilt University
Target Recruit Count
27034
Registration Number
NCT02625181
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

The Effects of Remifentanil and Remifentanil-Alfentanil Administration in Children

Not Applicable
Completed
Conditions
Adverse Effect of Other General Anesthetics
Interventions
Other: Sevoflurane
First Posted Date
2015-07-01
Last Posted Date
2015-07-07
Lead Sponsor
Hallym University Medical Center
Target Recruit Count
102
Registration Number
NCT02486926
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