Escitalopram
- Generic Name
- Escitalopram
- Brand Names
- Cipralex, Lexapro
- Drug Type
- Small Molecule
- Chemical Formula
- C20H21FN2O
- CAS Number
- 128196-01-0
- Unique Ingredient Identifier
- 4O4S742ANY
- Background
Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety. Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...
- Indication
Escitalopram is indicated for the acute and maintenance treatment of major depressive disorder (MDD) in adults and pediatric patients 12 years old and older and for the acute treatment of generalized anxiety disorder (GAD) in adults and pediatric patients 7 years old and older. It is additionally indicated for symptomatic relief of obsessive-compulsive disor...
- Associated Conditions
- Anxiety, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD)
- Associated Therapies
- -
Antidepressants Trial in Parkinson's Disease
- Conditions
- Interventions
- First Posted Date
- 2018-08-29
- Last Posted Date
- 2023-05-06
- Lead Sponsor
- University College, London
- Target Recruit Count
- 52
- Registration Number
- NCT03652870
- Locations
- 🇬🇧
Royal Free London NHS Foundation Trust, London, United Kingdom
A Prediction Study of Multiple Indexes of the Effect of Different Mechanisms of Antidepressants Treatment on Depression
- Conditions
- Interventions
- First Posted Date
- 2018-08-09
- Last Posted Date
- 2019-09-17
- Lead Sponsor
- Yuqi Cheng
- Target Recruit Count
- 200
- Registration Number
- NCT03623711
- Locations
- 🇨🇳
The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China
Biomarkers of Antidepressant Response and Suicidal Events in Depressed Youth
- First Posted Date
- 2018-06-06
- Last Posted Date
- 2019-04-04
- Lead Sponsor
- Seoul National University
- Target Recruit Count
- 152
- Registration Number
- NCT03547219
- Locations
- 🇰🇷
Seoul National University Hospital, Seoul, N/A = Not Applicable, Korea, Republic of
Impact of Escitalopram on Sperm DNA Fragmentation
- Conditions
- Interventions
- First Posted Date
- 2018-05-16
- Last Posted Date
- 2024-03-25
- Lead Sponsor
- Weill Medical College of Cornell University
- Target Recruit Count
- 70
- Registration Number
- NCT03527043
- Locations
- 🇺🇸
Weill Cornell Medicine, New York, New York, United States
Treatments for Anxiety: Meditation and Escitalopram
- Conditions
- Interventions
- First Posted Date
- 2018-05-11
- Last Posted Date
- 2022-01-11
- Lead Sponsor
- Georgetown University
- Target Recruit Count
- 276
- Registration Number
- NCT03522844
- Locations
- 🇺🇸
Georgetown University Medical Center, Washington, District of Columbia, United States
🇺🇸New York University, New York, New York, United States
🇺🇸Massachusetts General Hospital, Boston, Massachusetts, United States
Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
- Conditions
- Interventions
- Drug: Tranexamic acid (TXA)Drug: HydrocodoneDrug: labetalolDrug: metforminDrug: nifedipineDrug: oxycodoneDrug: clindamycinDrug: azithromycinDrug: escitalopramDrug: sertralineDrug: CiprofloxacinDrug: ondansetronDrug: DoxycyclineDrug: LevofloxacinDrug: MethylphenidateDrug: CitalopramDrug: SumatriptanDrug: CyclobenzaprineDrug: FurosemideDrug: RosuvastatinDrug: GabapentinDrug: HydrochlorothiazideDrug: HydroxyureaDrug: TrazodoneDrug: TopiramateDrug: ValganciclovirDrug: RemdesivirDrug: VenlafaxineDrug: VerapamilDrug: FluvoxamineDrug: AnakinraDrug: TocilizumabDrug: AmoxicillinDrug: BupropionDrug: BuprenorphineDrug: LevetiracetamDrug: ParoxetineDrug: Duloxetine
- First Posted Date
- 2018-04-27
- Last Posted Date
- 2024-12-17
- Lead Sponsor
- Duke University
- Target Recruit Count
- 1600
- Registration Number
- NCT03511118
- Locations
- 🇺🇸
Northwestern University, Chicago, Illinois, United States
🇺🇸Ann and Robert H. Lurie Childrens Hospital of Chicago, Chicago, Illinois, United States
🇺🇸Loma Linda University Health, Loma Linda, California, United States
Comparative Efficacy of Duloxetine vs Escitalopram in Patients With Fibromyalgia
- First Posted Date
- 2018-04-03
- Last Posted Date
- 2020-02-27
- Lead Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
- Target Recruit Count
- 200
- Registration Number
- NCT03487211
- Locations
- 🇵🇰
Pakistan Institute of Medical Sciences, Islamabad, Islamabad Capital Territory, Pakistan
Bariatric Surgery and Pharmacokinetics of Escitalopram
- Conditions
- First Posted Date
- 2018-03-09
- Last Posted Date
- 2023-03-27
- Lead Sponsor
- Norwegian University of Science and Technology
- Target Recruit Count
- 12
- Registration Number
- NCT03460379
- Locations
- 🇳🇴
St. Olavs University Hospital, Trondheim, Norway
Effect of Attention Training or SSRIs on Symptoms and Neural Activation in Social Anxiety
- Conditions
- Interventions
- First Posted Date
- 2017-11-17
- Last Posted Date
- 2022-02-01
- Lead Sponsor
- Tel Aviv University
- Target Recruit Count
- 105
- Registration Number
- NCT03346239
- Locations
- 🇮🇱
Tel Aviv University, Tel Aviv, Israel
Cognitive Dysfunction in MDD Patients
- First Posted Date
- 2017-06-14
- Last Posted Date
- 2019-01-10
- Lead Sponsor
- Oleg Levada
- Target Recruit Count
- 150
- Registration Number
- NCT03187093
- Locations
- 🇺🇦
State Institution "Zaporizhzhia Medical Academy of Postgraduate Education Ministry of Health of Ukraine", Zaporizhzhia, Ukraine
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.