Propofol
- Generic Name
- Propofol
- Brand Names
- Diprivan
- Drug Type
- Small Molecule
- Chemical Formula
- C12H18O
- CAS Number
- 2078-54-8
- Unique Ingredient Identifier
- YI7VU623SF
- Background
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.
- Indication
Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
- Associated Conditions
- -
- Associated Therapies
- Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
Use of S+Ketamine During Target-Controlled Intravenous Anaesthesia After Abdominal Hysterectomy
- Conditions
- MorphineAnesthesiaHysterectomyKetamine
- Interventions
- First Posted Date
- 2017-07-27
- Last Posted Date
- 2017-07-27
- Lead Sponsor
- KK Women's and Children's Hospital
- Target Recruit Count
- 90
- Registration Number
- NCT03231683
- Locations
- 🇸🇬
Kk Women'S and Children'S Hospital, Singapore, Singapore
Comparison Between Target-controlled Infusion of Propofol and Sevoflurane as Maintenance of Anesthesia to Hemodynamic Profile of Renal Transplant Recipient
- Conditions
- Renal Transplant Recipient Patients
- Interventions
- First Posted Date
- 2017-07-11
- Last Posted Date
- 2018-02-28
- Lead Sponsor
- Indonesia University
- Target Recruit Count
- 23
- Registration Number
- NCT03214653
- Locations
- 🇮🇩
Cipto Mangunkusumo Central National Hospital, Jakarta, DKI Jakarta, Indonesia
Bispectral Index (BIS) Values Required for an Adequate Depth of Anesthesia in Elderly Patients Using Propofol
- First Posted Date
- 2017-06-22
- Last Posted Date
- 2018-04-11
- Lead Sponsor
- Pontificia Universidad Catolica de Chile
- Target Recruit Count
- 12
- Registration Number
- NCT03195530
- Locations
- 🇨🇱
Division de Anestesia - Pontificia Universidad Catolica de Chile, Santiago, Region Metropolitana, Chile
The Effects of General Anesthetics on Lymphocytes in Patients Undergoing Colorectal Cancer Resection and Mechanism Involved
- Conditions
- Survival RateLymphocyte DestructionColorectal Cancer MetastaticGeneral Anesthetics ToxicityMolecular Mechanism of Pharmacological Action
- Interventions
- First Posted Date
- 2017-06-21
- Last Posted Date
- 2017-11-06
- Lead Sponsor
- Guizhi Du
- Target Recruit Count
- 260
- Registration Number
- NCT03193710
- Locations
- 🇨🇳
West China Hospital of Sichuan University, Department of Anesthesiology, Chengdu, Sichuan, China
Early Cognitive Function in Elderly Patients After Laser Laryngeal Surgery: Des vs Prop
- First Posted Date
- 2017-06-21
- Last Posted Date
- 2018-07-27
- Lead Sponsor
- Eye & ENT Hospital of Fudan University
- Target Recruit Count
- 70
- Registration Number
- NCT03194074
- Locations
- 🇨🇳
Otorhinolaryngology Department of Affiliated Eye and ENT Hospital, Fudan University, Shanghai, China, Shanghai, Shanghai, China
The Preventive Effects of Sub Hypnotic Dose of Propofol for Nausea and Vomiting Induced by Hemabate
- First Posted Date
- 2017-06-14
- Last Posted Date
- 2018-10-23
- Lead Sponsor
- West China Second University Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT03185156
- Locations
- 🇨🇳
West China Second University Hospital, Chengdu, Sichuan, China
Transition to Propofol After Sevoflurane Anaesthesia to Prevent Emergence Agitation
- First Posted Date
- 2017-06-07
- Last Posted Date
- 2018-11-28
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 70
- Registration Number
- NCT03179293
- Locations
- 🇪🇬
Assiut University hospital, Assiut, Asyut Governorate, Egypt
Appropriate Compatibility of Propofol and Sevoflurane for Orthopaedic Surgery of Patients With MCI
- First Posted Date
- 2017-05-24
- Last Posted Date
- 2018-05-25
- Lead Sponsor
- The Third Central Clinical College of Tianjin Medical University
- Target Recruit Count
- 100
- Registration Number
- NCT03165396
- Locations
- 🇨🇳
Third Central Hospital of Tianjin, Tianjin, Tianjin, China
Analysis of Change of Optic Nerve Sheath Diameter in Robot Assisted Laparoscopic Radical Prostatectomy
- Conditions
- Optic Nerve Sheath DiameterRobot Assisted Laparoscopic Radical Prostatectomy
- Interventions
- First Posted Date
- 2017-05-15
- Last Posted Date
- 2018-04-18
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT03152981
- Locations
- 🇰🇷
Seoul National Univ. Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea, Republic of
Comparison of Propofol and Sevoflurane as Maintaining Anesthetics During General Anesthesia of Cesarean Section
- First Posted Date
- 2017-05-11
- Last Posted Date
- 2018-06-12
- Lead Sponsor
- Tao Zhang
- Target Recruit Count
- 60
- Registration Number
- NCT03149588
- Locations
- 🇨🇳
First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
Drug Development Updates
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