Propofol

Generic Name: Propofol

Brand Names: Diprivan

Drug Type: Small Molecule

Chemical Formula: C_₁₂H_₁₈O

CAS Number: 2078-54-8

Unique Ingredient Identifier: YI7VU623SF

Background: Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.

Indication: Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.

Associated Conditions: -

Associated Therapies: Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy

Clinical Trials

Anaesthesia for Laparoscopic Sleeve Gastrectomy

Not Applicable

Completed

Conditions: Obese

Interventions: Drug: Propofol
Drug: Desflurane
Drug: Remifentanil
Drug: Dexmedetomidine

First Posted Date: 2017-01-24

Last Posted Date: 2020-09-16

Lead Sponsor: Menoufia University

Target Recruit Count: 100

Registration Number: NCT03029715

Anaesthetic and Pediatric Living Related Liver Transplantation

Not Applicable

Conditions: Children
Liver Transplantation

Interventions: Drug: Sevoflurane
Drug: Propofol

First Posted Date: 2017-01-19

Last Posted Date: 2017-01-19

Lead Sponsor: Tianjin First Central Hospital

Target Recruit Count: 60

Registration Number: NCT03024840

Locations: 🇨🇳
No.24 Fukang Road,Nankai District, Tianjin, Tianjin, China

Neurobiological and Cognitive Changes Following Exposure to Either Sevoflurane- or Propofol-based Anesthesia in Children

Phase 3

Completed

Conditions: Cognitive Change
Behavior

Interventions: Drug: Sevoflurane
Drug: Propofol
Drug: Ametop
Drug: Ondansetron

First Posted Date: 2017-01-16

Last Posted Date: 2020-03-26

Lead Sponsor: University of Calgary

Target Recruit Count: 50

Registration Number: NCT03022240

Locations: 🇨🇦
University of Calgary, Calgary, Alberta, Canada

IOP Changes With Different Anesthetic Agents During Laparoscopic Colorectal Surgery

Not Applicable

Completed

Conditions: Intraocular Pressure

Interventions: Drug: Desflurane
Drug: Propofol

First Posted Date: 2017-01-10

Last Posted Date: 2017-04-26

Lead Sponsor: Saint Vincent's Hospital, Korea

Target Recruit Count: 50

Registration Number: NCT03016234

Locations: 🇰🇷
Saint Vincent's Hospital, Korea, Suwon, Gyonggido, Korea, Republic of

Ultrasonography for Prediction of Difficult Intubation and Prediction of Endotracheal Tube Size

Not Applicable

Conditions: Intubation; Difficult or Failed

Interventions: Device: Ultrasonography
Drug: Sevoflurane
Drug: intravenous midazolam
Drug: Propofol
Drug: fentanyl and rocuronium

First Posted Date: 2017-01-06

Last Posted Date: 2017-01-06

Lead Sponsor: Istanbul University

Target Recruit Count: 150

Registration Number: NCT03013036

Locations: 🇹🇷
Istanbul University Cerrahpasa Medical Faculty, Istanbul, Fatih, Turkey

Preoxygenation With Optiflow™ in Morbidly Obese Patients is Superior to Face Mask

Not Applicable

Withdrawn

Conditions: Obesity, Morbid

Interventions: Device: facemask
Device: Optiflow F&P 850™ System
Drug: Rocuronium
Drug: Propofol
Drug: Fentanyl
Drug: Midazolam
Device: C-MAC Premium Video Intubation Platform-KARL STORZ