Ramosetron

Generic Name
Ramosetron
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C17H17N3O
CAS Number
132036-88-5
Unique Ingredient Identifier
7ZRO0SC54Y
Background

Ramosetron is a serotonin 5-HT3 receptor antagonist commonly employed to treat nausea and vomiting, in addition to certain diarrheal conditions. It is believed to have higher potency and longer antiemetic action than other 1st generation 5-HT3 antagonists such as ondansetron. Currently, ramosetron is only approved for use Japan and in certain Southeast Asian...

Indication

For the treatment of nausea and vomiting and diarrhea-predominant irritable bowel syndrome in males.

Associated Conditions
Gastrointestinal Symptoms caused by cancer treatment
Associated Therapies
-
Clinical Trials
Related News

Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis

Not Applicable
Completed
Conditions
Postoperative Nausea and Vomiting
Interventions
Procedure: Automated recommendation at the start of the case
Procedure: Automated notification at the start of surgery
Procedure: Automated notification at the end of surgery
Device: Anesthesia Information Management System (AIMS)
Device: Perioperative Data Warehouse (PDW)
Procedure: General anesthesia
Procedure: Elective surgery
Drug: Propofol
Drug: Sevoflurane
Drug: Isoflurane
Drug: Desflurane
Drug: Scopolamine
Drug: Droperidol
Drug: Haloperidol
Drug: Dexamethasone
Drug: Promethazine
Drug: Meclizine
Drug: Aprepitant
Drug: Metoclopramide
Drug: Fentanyl
Drug: Sufentanil
Drug: Alfentanil
Drug: Remifentanil
Drug: Morphine
Drug: Meperidine
Drug: Hydromorphone
Drug: Methadone
Drug: Oxycodone
Drug: Oxymorphone
Drug: Hydrocodone
Drug: Ketamine
Drug: Ondansetron
Drug: Granisetron
Drug: Dolasetron mesylate
Drug: Palonosetron
Drug: Tropisetron
Drug: Ramosetron
First Posted Date
2015-12-09
Last Posted Date
2019-03-07
Lead Sponsor
Vanderbilt University
Target Recruit Count
27034
Registration Number
NCT02625181
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

The Effects of Gabapentin and Ramosetron on Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgery

First Posted Date
2015-11-30
Last Posted Date
2015-11-30
Lead Sponsor
Hallym University Medical Center
Target Recruit Count
120
Registration Number
NCT02617121
Locations
🇰🇷

Hallym University Sacred Heart Hospital, Anyang-si, Gyeonggi-do, Korea, Republic of

Special Drug Use Surveillance of Irribow in Female Patients

First Posted Date
2015-11-24
Last Posted Date
2024-10-21
Lead Sponsor
Astellas Pharma Inc
Target Recruit Count
793
Registration Number
NCT02612649

Analgesia Effects of Nalbuphine vs Sulfentanil

First Posted Date
2015-11-13
Last Posted Date
2015-11-13
Lead Sponsor
Fudan University
Target Recruit Count
80
Registration Number
NCT02604797

Postoperative Nausea and Vomiting: Ramosetron Plus Aprepitant vs Palonosetron Plus Aprepitant

First Posted Date
2015-11-05
Last Posted Date
2017-04-25
Lead Sponsor
Kyungpook National University Hospital
Target Recruit Count
88
Registration Number
NCT02597907

Comparison of Palonosetron and Ramosetron for Preventing Patient-controlled Analgesia Related Nausea and Vomiting Following Spine Surgery; Association With ABCB1 Polymorphism

First Posted Date
2015-06-24
Last Posted Date
2017-10-27
Lead Sponsor
Yonsei University
Target Recruit Count
300
Registration Number
NCT02480088
Locations
🇰🇷

Department of Anesthesiology and Pain Medicine and Anesthesia, Seoul, Korea, Republic of

Anti Emetic Efficacy of Combination of Ramosetron and Premixture of Naloxone With Patient-controlled Analgesia

First Posted Date
2015-04-14
Last Posted Date
2016-02-22
Lead Sponsor
Kyungpook National University Hospital
Target Recruit Count
90
Registration Number
NCT02416115

The Efficacy and Safety of Ramosetron in Patients Undergoing Off Pump Coronary Artery Bypass Surgery

First Posted Date
2014-05-15
Last Posted Date
2015-11-20
Lead Sponsor
Seoul National University Hospital
Target Recruit Count
114
Registration Number
NCT02139241
Locations
🇰🇷

Seoul National University Hospital, Seoul, Korea, Republic of

Long Term Prevention of Nausea and Vomiting in Gynecologic Laparoscopy

First Posted Date
2013-12-13
Last Posted Date
2013-12-13
Lead Sponsor
National Health Insurance Service Ilsan Hospital
Target Recruit Count
128
Registration Number
NCT02011659
Locations
🇰🇷

National Health Insurance Service Ilsan Hospital, Goyang-si, Korea, Republic of

Comparison of Palonosetron and Ramosetron for Preventing Patient-controlled Analgesia Related Nausea and Vomiting Following Spine Surgery

Not Applicable
Completed
Conditions
Postoperative Nausea and Vomiting
Interventions
Drug: ramosetron
Drug: palonosetron
First Posted Date
2013-04-08
Last Posted Date
2014-02-19
Lead Sponsor
Yonsei University
Target Recruit Count
196
Registration Number
NCT01825733
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