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Dexmedetomidine

Generic Name
Dexmedetomidine
Brand Names
Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
Drug Type
Small Molecule
Chemical Formula
C13H16N2
CAS Number
113775-47-6
Unique Ingredient Identifier
67VB76HONO
Background

An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.

Indication

Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.

Associated Conditions
Agitation, Alcohol Withdrawal Syndrome
Associated Therapies
-

Dexmedetomidine Versus Magnesium Sulphate for Caesarean Delivery

Phase 3
Conditions
Cesarean Section
Interventions
First Posted Date
2017-03-01
Last Posted Date
2017-03-01
Lead Sponsor
Assiut University
Target Recruit Count
78
Registration Number
NCT03067896
Locations
🇪🇬

Ahmed Talaat Ahmed, Assiut, Egypt

Intraperitoneal Dexmedetomidine for Post-laparoscopic Appendicectomy Pain Management in Children

Phase 4
Conditions
Pain, Postoperative
Interventions
First Posted Date
2017-03-01
Last Posted Date
2017-03-01
Lead Sponsor
Zagazig University
Target Recruit Count
56
Registration Number
NCT03067740
Locations
🇸🇦

Ali Elnabtity, Jeddah, Saudi Arabia

Ketamine Versus Dexmedetomidine With Local Anesthetic in TAP Block

Phase 2
Completed
Conditions
Lower Abdominal Cancer
Postoperative Analgesia
Interventions
First Posted Date
2017-02-23
Last Posted Date
2017-07-05
Lead Sponsor
Assiut University
Target Recruit Count
90
Registration Number
NCT03060070
Locations
🇪🇬

South Egypt Cancer Institute, Assiut, Assiut University, Egypt

The Effect of Dexmedetomidine Infusion on Post-operative Cognitive Function and Oxidative Stress in Cardiac Surgery

Phase 4
Completed
Conditions
Oxidative Stress
Cognition Disorders
Interventions
First Posted Date
2017-02-16
Last Posted Date
2018-06-19
Lead Sponsor
Chulalongkorn University
Target Recruit Count
100
Registration Number
NCT03054857

Efficacy and Safety of Dexmedetomidine Added to Modified Pectoral's Block in Breast Cancer Patients

Phase 3
Conditions
Breast Cancer Patients
Interventions
First Posted Date
2017-02-08
Last Posted Date
2017-02-27
Lead Sponsor
South Egypt Cancer Institute
Target Recruit Count
60
Registration Number
NCT03046238
Locations
🇪🇬

South Egypt Cancer Institute, Assiut University, Assiut, Egypt., Assuit, Egypt

Perineural Dexmedetomidine in Adductor Canal Block

Phase 4
Completed
Conditions
Arthroscopic Medial Meniscectomy
Interventions
Drug: Normal saline
Drug: Dexmedetomidine
First Posted Date
2017-01-25
Last Posted Date
2019-01-15
Lead Sponsor
Cairo University
Target Recruit Count
40
Registration Number
NCT03030950
Locations
🇪🇬

Cairo University, Cairo, Egypt

Dexmedetomidine vs Midazolam on Resting Energy Expenditure in Critically Ill Patients

Phase 4
Completed
Conditions
Mechanical Ventilation
Midazolam
Sedation
Dexmedetomidine
Interventions
First Posted Date
2017-01-25
Last Posted Date
2018-03-27
Lead Sponsor
Cairo University
Target Recruit Count
30
Registration Number
NCT03030911
Locations
🇪🇬

Cairo University, Cairo, Egypt

Anaesthesia for Laparoscopic Sleeve Gastrectomy

Not Applicable
Completed
Conditions
Obese
Interventions
First Posted Date
2017-01-24
Last Posted Date
2020-09-16
Lead Sponsor
Menoufia University
Target Recruit Count
100
Registration Number
NCT03029715

Effect of Intrathecal Morphine, Dexmedetomidine or Both in Combination to Bupivacaine on Immunity

Phase 1
Conditions
Immune System Suppression
Interventions
First Posted Date
2017-01-19
Last Posted Date
2021-01-14
Lead Sponsor
Assiut University
Target Recruit Count
30
Registration Number
NCT03024957
Locations
🇪🇬

Assiut University, Assiut, Egypt

The Effect of Orexin on Delayed Emergence of General Anesthesia in Dexmedetomidine

Not Applicable
Completed
Conditions
Anesthesia
Interventions
First Posted Date
2017-01-19
Last Posted Date
2021-06-23
Lead Sponsor
General Hospital of Ningxia Medical University
Target Recruit Count
51
Registration Number
NCT03025295
Locations
🇨🇳

Anesthesiology department of General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China

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