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Dexmedetomidine

Generic Name
Dexmedetomidine
Brand Names
Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
Drug Type
Small Molecule
Chemical Formula
C13H16N2
CAS Number
113775-47-6
Unique Ingredient Identifier
67VB76HONO
Background

An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.

Indication

Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.

Associated Conditions
Agitation, Alcohol Withdrawal Syndrome
Associated Therapies
-
Clinical Trials
Related News

Protective Effects of Dexmedetomidine on Myocardial Injury During Liver Transplantation

Not Applicable
Conditions
Evidence of Liver Transplantation
Myocardial Injury
Interventions
Drug: Dexmedetomidine
Drug: Normal saline
First Posted Date
2017-01-06
Last Posted Date
2017-01-06
Lead Sponsor
Tianjin First Central Hospital
Target Recruit Count
100
Registration Number
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Locations
🇨🇳

No.24 Fukang Road,Nankai District, Tianjin, Tianjin, China

Sedation by Dexmedetomidine and Propofol

Not Applicable
Completed
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Anesthesia, Spinal
Interventions
Drug: Propofol
Drug: Dexmedetomidine
First Posted Date
2016-12-15
Last Posted Date
2017-09-14
Lead Sponsor
Seoul National University Bundang Hospital
Target Recruit Count
52
Registration Number
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Locations
🇰🇷

Seoul National University Bundang Hospital, Seongnam, Gyeonggi, Korea, Republic of

Conscious Sedation for Epilepsy Surgery

First Posted Date
2016-12-09
Last Posted Date
2020-10-09
Lead Sponsor
Menoufia University
Target Recruit Count
60
Registration Number
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Safety and Efficacy of Intranasal Dexmedetomidine

Phase 4
Conditions
Safety and Efficacy of Intranasal Dexmedetomidine
Interventions
Drug: Midazolam Hydrochloride
Drug: Dexmedetomidine
Drug: Nitrous Oxide
First Posted Date
2016-12-07
Last Posted Date
2016-12-07
Lead Sponsor
Bon Secours Pediatric Dental Associates
Target Recruit Count
100
Registration Number
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Locations
🇺🇸

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Dexmedetomidine on Basal Ganglia Neuronal Activity in Parkinson's Disease

Phase 4
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Dexmedetomidine
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Interventions
Drug: Dexmedetomidine
First Posted Date
2016-12-05
Last Posted Date
2018-05-11
Lead Sponsor
Clinica Universidad de Navarra, Universidad de Navarra
Target Recruit Count
12
Registration Number
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Locations
🇪🇸

Clínica Universidad de Navarra, Pamplona, Navarra, Spain

Effect of Sedatives on Regional Cerebral Oxygen Saturation

Not Applicable
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Interventions
Drug: Midazolam
Drug: Dexmedetomidine
First Posted Date
2016-11-17
Last Posted Date
2019-02-15
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Registration Number
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Dexmedetomidine Versus Standard Clinical Practice During Non Invasive Mechanical Ventilation

Phase 4
Conditions
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Interventions
Procedure: Standard Clinical Practice
Drug: Dexmedetomidine
First Posted Date
2016-11-08
Last Posted Date
2022-03-11
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120
Registration Number
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Locations
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Araba University Hospital, Vitoria, Álava, Spain

The Synergistic Effect of Dexmedetomidine on Propofol for Sedation for Pediatric Endoscopy

Phase 4
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Interventions
Drug: Propofol (Group P)
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First Posted Date
2016-11-02
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2024-05-10
Lead Sponsor
Keira Mason
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39
Registration Number
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Boston Children's Hospital, Boston, Massachusetts, United States

Paravertebral Morphine Versus Dexmedetomidine on Acute and Chronic Postmastectomy Pain

Phase 1
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2016-10-18
Last Posted Date
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Target Recruit Count
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Registration Number
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Locations
🇪🇬

Assiut University, Assiut, Iorg0006563, Egypt

The Effect of Remifentanil-dexmedetomidine Compared With Remifentanil-midazolam on Patient's Satisfaction

Not Applicable
Completed
Conditions
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Interventions
Drug: dexmedetomidine
Drug: midazolam
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First Posted Date
2016-10-10
Last Posted Date
2019-01-10
Lead Sponsor
Yonsei University
Target Recruit Count
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Registration Number
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Locations
🇰🇷

Department of Anaesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea, Republic of

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