Meperidine

Generic Name: Meperidine

Brand Names: Demerol

Drug Type: Small Molecule

Chemical Formula: C_₁₅H_₂₁NO_₂

CAS Number: 57-42-1

Unique Ingredient Identifier: 9E338QE28F

Background: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.

Indication: Used to control moderate to severe pain.

Associated Conditions: Severe Pain

Associated Therapies: Anesthesia therapy, Anesthetic premedication therapy, General Anesthesia, Local Anaesthesia therapy, Perioperative management therapy

Clinical Trials

Comparison of Meperidine and Fentanyl on Pain Scale and QOL in Brachytherapy

Phase 4

Completed

Conditions: Pain
Quality of Life

Interventions: Drug: Meperidine
Drug: Fentanyl

First Posted Date: 2016-02-18

Last Posted Date: 2017-06-01

Lead Sponsor: Chulabhorn Cancer Center

Target Recruit Count: 40

Registration Number: NCT02684942

Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis

Not Applicable

Completed

Conditions: Postoperative Nausea and Vomiting

Interventions: Procedure: Automated recommendation at the start of the case
Procedure: Automated notification at the start of surgery
Procedure: Automated notification at the end of surgery
Device: Anesthesia Information Management System (AIMS)
Device: Perioperative Data Warehouse (PDW)
Procedure: General anesthesia
Procedure: Elective surgery
Drug: Propofol
Drug: Sevoflurane
Drug: Isoflurane
Drug: Desflurane
Drug: Scopolamine
Drug: Droperidol
Drug: Haloperidol
Drug: Dexamethasone
Drug: Promethazine
Drug: Meclizine
Drug: Aprepitant
Drug: Metoclopramide
Drug: Fentanyl
Drug: Sufentanil
Drug: Alfentanil
Drug: Remifentanil
Drug: Morphine
Drug: Meperidine
Drug: Hydromorphone
Drug: Methadone
Drug: Oxycodone
Drug: Oxymorphone
Drug: Hydrocodone
Drug: Ketamine
Drug: Ondansetron
Drug: Granisetron
Drug: Dolasetron mesylate
Drug: Palonosetron
Drug: Tropisetron
Drug: Ramosetron

First Posted Date: 2015-12-09

Last Posted Date: 2019-03-07

Lead Sponsor: Vanderbilt University

Target Recruit Count: 27034

Registration Number: NCT02625181

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

Effect of Spinal Dexamethasone During Transuretheral Prostatectomy

Phase 2

Completed

Conditions: Postspinal Shivering

Interventions: Drug: Normal saline
Drug: Dexamethasone
Drug: Pethidine

First Posted Date: 2015-12-02

Last Posted Date: 2016-09-15

Lead Sponsor: Assiut University

Target Recruit Count: 90

Registration Number: NCT02619019

Locations: 🇪🇬
Seham Mohamed Moeen Ibrahim, Asyut, Egypt

Paracetamol for Intrapartum Analgesia

Phase 2

Conditions: Analgesia, Obstetrical

Interventions: Drug: Paracetamol
Drug: Pethidine

First Posted Date: 2015-10-16

Last Posted Date: 2015-10-16

Lead Sponsor: Ain Shams Maternity Hospital

Target Recruit Count: 104

Registration Number: NCT02578251

Hyoscine ButylBromide for Intrapartum Analgesia

Phase 2

Conditions: Analgesia, Obstetrical

Interventions: Drug: Hyoscine
Drug: Pethidine

First Posted Date: 2015-09-23

Last Posted Date: 2015-09-23

Lead Sponsor: Ain Shams Maternity Hospital

Target Recruit Count: 104

Registration Number: NCT02557087

Tenoxicam for Intrapartum Analgesia

Phase 2

Conditions: Analgesia
Obstetrical

Interventions: Drug: Tenoxicam
Drug: Pethidine

First Posted Date: 2015-09-15

Last Posted Date: 2015-09-15

Lead Sponsor: Ain Shams Maternity Hospital

Target Recruit Count: 100

Registration Number: NCT02549118

A Non-inferiority Trial on Pain Relief During Oocyte Retrieval

Phase 4

Completed

Conditions: Infertility

Interventions: Drug: pethidine
Drug: fentanyl
Drug: Midazolam
Drug: Diazepam

First Posted Date: 2015-07-10

Last Posted Date: 2019-03-05

Lead Sponsor: Kwong Wah Hospital

Target Recruit Count: 170

Registration Number: NCT02494180

The Effect of Different Sedation Regimes on Cognitive Function in Lower Gastrointestinal System Endoscopy

Phase 4

Completed

Conditions: Gastrointestinal Dysfunction
Alteration of Cognitive Function

Interventions: Drug: Midazolam
Drug: Remifentanil
Drug: Meperidine
Drug: Propofol

First Posted Date: 2015-07-01

Last Posted Date: 2020-09-03

Lead Sponsor: Ufuk University

Target Recruit Count: 103

Registration Number: NCT02486328

Nefopam vs Tramadol in the Prevention of Post Anaesthetic Shivering

Phase 2

Conditions: Post Anaesthetic Shivering

Interventions: Drug: Nefopam
Drug: Tramadol
Drug: Metoclopramide
Drug: Ranitidine
Drug: Pethidine
Drug: Ephedrine
Drug: oxytocin

First Posted Date: 2015-05-12

Last Posted Date: 2018-07-17

Lead Sponsor: Lagos State Health Service Commission

Target Recruit Count: 130

Registration Number: NCT02441673

A Randomised Controlled Trial of Remifentanil Intravenous Patient Controlled Analgesia (PCA) Versus Intramuscular Pethidine for Pain Relief in Labour

Phase 4

Completed

Conditions: Pain Relief in Labour

Interventions: Drug: Pethidine
Drug: Remifentanil

First Posted Date: 2014-07-01

Last Posted Date: 2018-10-15

Lead Sponsor: University of Birmingham

Target Recruit Count: 401

Registration Number: NCT02179294

Locations: 🇬🇧
Birmingham Clinical Trials Unit, Birmingham, West Midlands, United Kingdom

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