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Tetracaine

Generic Name
Tetracaine
Brand Names
Ametop, Cetacaine, Kovanaze, One Touch Reformulated Apr 2009, Pliaglis, Synera, Zap
Drug Type
Small Molecule
Chemical Formula
C15H24N2O2
CAS Number
94-24-6
Unique Ingredient Identifier
0619F35CGV
Background

Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.

Indication

Ophthalmic tetracaine is indicated for the for procedures requiring a rapid and short- acting topical ophthalmic anesthetic.

The combination lidocaine and tetracaine patch is indicated for local dermal analgesia for superficial dermatological procedures and superficial venous access. The combination lidocaine and tetracaine cream is intended to provide topical local analgesia for superficial dermatological procedures.

Associated Conditions
Dermabrasion, Haemorrhoids, Insect Bites, Rash caused by poison ivy, Sunburn, Minor burns
Associated Therapies
Local Anaesthesia therapy, Local Anesthesia of the Skin

Topical Anesthesia and Intra-arterial Chemotherapy for Retinoblastoma

Early Phase 1
Withdrawn
Conditions
Hemodynamic Instability
Interventions
First Posted Date
2016-11-04
Last Posted Date
2018-04-20
Lead Sponsor
University of Miami
Registration Number
NCT02955524

Postoperative Analgesic Efficacy of Tetracaine Hydrochloride Gel

Not Applicable
Completed
Conditions
Hysteroscopy
Interventions
First Posted Date
2016-08-11
Last Posted Date
2016-10-12
Lead Sponsor
Wenzhou Medical University
Target Recruit Count
84
Registration Number
NCT02863679
Locations
🇨🇳

the 1st Affiliated Hospital of Wenzhou Medical College, Wenzhou, Zhejiang, China

Treatment of Corneal Abrasions With Topical Tetracaine

Phase 2
Conditions
Corneal Abrasion
Interventions
Other: Normal Saline
First Posted Date
2016-05-13
Last Posted Date
2016-05-13
Lead Sponsor
New York Presbyterian Brooklyn Methodist Hospital
Target Recruit Count
120
Registration Number
NCT02771392
Locations
🇺🇸

New York Methodist Hospital, Brooklyn, New York, United States

Ametop - Friend and Foe A Prospective Study of the Incidence of Adverse Reactions With Ametop

Completed
Conditions
Adverse Drug Event
First Posted Date
2016-04-25
Last Posted Date
2016-04-25
Lead Sponsor
KK Women's and Children's Hospital
Target Recruit Count
192
Registration Number
NCT02750137

Decision Support for Intraoperative Low Blood Pressure

Not Applicable
Completed
Conditions
Hypotension
Interventions
Procedure: Attending real-time decision support
Procedure: In-room real-time decision support
Procedure: Attending feedback emails
Procedure: In-room provider feedback emails
Device: Anesthesia Information Management System (AIMS)
Device: Perioperative Data Warehouse (PDW)
Procedure: General anesthesia
Device: Pager system
Procedure: Central neuraxial anesthesia
Procedure: Non-cardiac surgery
Drug: Ringer's lactate
Drug: Hydroxyethyl starch solutions
Drug: Packed Red Blood Cells
Drug: Albumin solutions
First Posted Date
2016-04-04
Last Posted Date
2019-05-16
Lead Sponsor
Vanderbilt University Medical Center
Target Recruit Count
22435
Registration Number
NCT02726620
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Dorsal Penile Nerve Block for Rigid Cystoscopy in Men

Not Applicable
Completed
Conditions
Pain
Interventions
Procedure: Dorsal Penile Nerve Block
First Posted Date
2015-07-20
Last Posted Date
2020-03-31
Lead Sponsor
West China Hospital
Target Recruit Count
258
Registration Number
NCT02502487
Locations
🇨🇳

West China Hospital of Sichuan University, Department of Anesthesiology, Chengdu, Sichuan, China

Effect of Tetracaine on Pain Management and Corneal Healing in Patients With Acute Corneal Abrasion

Phase 3
Withdrawn
Conditions
Corneal Abrasion
Interventions
Drug: Normal Saline placebo drops
First Posted Date
2015-06-29
Last Posted Date
2018-06-04
Lead Sponsor
Queen's University
Registration Number
NCT02483897

Comparison of Anesthetic Efficacy of Bilateral and Unillateral Application of Kovacaine Mist in Healthy Volunteers

Phase 1
Completed
Conditions
Anesthesia
Interventions
First Posted Date
2015-05-29
Last Posted Date
2016-11-10
Lead Sponsor
St. Renatus, LLC
Target Recruit Count
48
Registration Number
NCT02457806
Locations
🇺🇸

Jean Brown Research, Salt Lake City, Utah, United States

Evaluation of Deep Topical Fornix Nerve Block Versus Topical Anaesthesia Procedure

Not Applicable
Conditions
Local Anesthesia
Satisfaction
Interventions
First Posted Date
2014-07-22
Last Posted Date
2014-07-22
Lead Sponsor
Cairo University
Target Recruit Count
102
Registration Number
NCT02196441
Locations
🇸🇦

Magrabi Aseer ,KSA, Khamis Mushayt, West, Saudi Arabia

Efficacy and Safety Assessment of Intracameral Injection of T2380 in Cataract Surgery

Phase 3
Completed
Conditions
Cataract
Interventions
First Posted Date
2014-04-02
Last Posted Date
2014-11-14
Lead Sponsor
Laboratoires Thea
Target Recruit Count
609
Registration Number
NCT02101359
Locations
🇫🇷

Laboratoires Thea, Clermont- Ferrand, France

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