MedPath

Dexmedetomidine

Generic Name
Dexmedetomidine
Brand Names
Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
Drug Type
Small Molecule
Chemical Formula
C13H16N2
CAS Number
113775-47-6
Unique Ingredient Identifier
67VB76HONO
Background

An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.

Indication

Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.

Associated Conditions
Agitation, Alcohol Withdrawal Syndrome
Associated Therapies
-
Clinical Trials
Related News

Dexmedetomidine and Fentanyl Versus Midazolam and Remifentanil for Sedation in Patients Undergoing Ablation Procedures

Not Applicable
Terminated
Conditions
Tachyarrhythmia
Interventions
Drug: Remifentanil Group
Drug: Dexmedetomidine group
First Posted Date
2018-03-01
Last Posted Date
2019-05-16
Lead Sponsor
University Health Network, Toronto
Target Recruit Count
6
Registration Number
NCT03451227
Locations
🇨🇦

Toronto General Hospital, Univerity health Network, Toronto, Ontario, Canada

Dexmedetomidine and 5-year Outcome in Elderly Patients After Surgery

Not Applicable
Completed
Conditions
Aged
Operative
Delirium
Dexmedetomidine
Mortality
Long-term Survivors
Interventions
Drug: dexmedetomidine
Drug: placebo
First Posted Date
2018-02-19
Last Posted Date
2019-06-21
Lead Sponsor
Peking University First Hospital
Target Recruit Count
700
Registration Number
NCT03436472
Locations
🇨🇳

Peking University First Hospital, Beijing, China

Dexmedetomidine Versus Fentanyl Plus Bupivacaine for Epidural Analgesia With General Anesthesia for Lumbar Disc Operations

Phase 4
Completed
Conditions
Anesthesia
Interventions
Drug: Bupivacaine
Drug: Fentanyl
Drug: Dexmedetomidine
First Posted Date
2018-02-19
Last Posted Date
2018-09-27
Lead Sponsor
Ain Shams University
Target Recruit Count
80
Registration Number
NCT03438240
Locations
🇪🇬

Ain Shams University hospitals, Cairo, Egypt

Designing Optimal Prevention and Management of Postoperative Nausea and Emesis for Patients Undergoing Laparoscopic Sleeve Gastrectomy

First Posted Date
2018-02-15
Last Posted Date
2024-02-14
Lead Sponsor
Stony Brook University
Target Recruit Count
83
Registration Number
NCT03435003
Locations
🇺🇸

Stony Brook University Hospital, Stony Brook, New York, United States

The Effect of Dexmedetomidine on Kidney Perfusion in Paediatric Patients

Phase 2
Conditions
Congenital Heart Disease
Interventions
Drug: Dexmedetomidine
First Posted Date
2018-02-08
Last Posted Date
2018-02-08
Lead Sponsor
Mai Madkour
Target Recruit Count
40
Registration Number
NCT03425734
Locations
🇪🇬

Pediatric University Hospitals, Cairo, Outside US And Canada, Egypt

The Effects of Dexmedetomidine on Intravenous Anesthetic Requirements for Children Undergoing Dental Procedures

Phase 4
Completed
Conditions
Anesthetic Sparing
Interventions
Drug: Normal saline
Drug: Dexmedetomidine
First Posted Date
2018-02-06
Last Posted Date
2024-04-22
Lead Sponsor
University of British Columbia
Target Recruit Count
88
Registration Number
NCT03422978
Locations
🇨🇦

BC Children's Hospital - Department of Anesthesia, Vancouver, British Columbia, Canada

Pharmacokinetic Study of Intranasal Dexmedetomidine in Pediatric Patients With Congenital Heart Disease

Phase 1
Terminated
Conditions
Congenital Heart Disease
Dexmedetomidine
Interventions
Drug: Dexmedetomidine
First Posted Date
2018-01-31
Last Posted Date
2024-03-22
Lead Sponsor
Children's Hospital of Philadelphia
Target Recruit Count
28
Registration Number
NCT03417999
Locations
🇺🇸

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

Suprazygomatic Block in Cleft Palate Surgery in Children

Phase 2
Completed
Conditions
Cleft Palate
Interventions
Drug: Bupivacaine
Drug: Dexmedetomidine
Drug: paracetamol
First Posted Date
2018-01-26
Last Posted Date
2018-09-24
Lead Sponsor
Assiut University
Target Recruit Count
80
Registration Number
NCT03412474
Locations
🇪🇬

Assiut University Hospital, Assiut, Egypt

Sedation Strategies for Therapeutic Bronchoscopy

Not Applicable
Terminated
Conditions
Bronchoscopy
Sedation
Interventions
Drug: Dexmedetomidine
Device: Laryngeal mask
Drug: Remifentanil
First Posted Date
2018-01-23
Last Posted Date
2019-06-12
Lead Sponsor
Changhai Hospital
Target Recruit Count
20
Registration Number
NCT03406546
Locations
🇨🇳

Faculty of Anesthesiology, Changhai Hospital, Shanghai, Shanghai, China

Sedation Strategies for Diagnostic Bronchoscopy

Not Applicable
Terminated
Conditions
Sedation
Bronchoscopy
Interventions
Drug: Midazolam
Drug: Dexmedetomidine
Drug: Fentanyl
Drug: Remifentanil
Drug: Propofol
First Posted Date
2018-01-23
Last Posted Date
2019-06-12
Lead Sponsor
Changhai Hospital
Target Recruit Count
28
Registration Number
NCT03406533
Locations
🇨🇳

Faculty of Anesthesiology, Changhai Hospital, Shanghai, Shanghai, China

© Copyright 2025. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy