Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
Renal Protection of Intravenous Dexmedetomidine During Radical Cystectomy
- First Posted Date
- 2017-08-29
- Last Posted Date
- 2020-09-09
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 100
- Registration Number
- NCT03265470
- Locations
- 🇪🇬
Mansoura university, Mansourah, Dakahlia, Egypt
Caudal Combination of Dexamethasone and/or Dexmedetomidine to Bupivacaine in Pediatric Hypospadias Surgery
- Conditions
- Caudal Block
- Interventions
- First Posted Date
- 2017-08-25
- Last Posted Date
- 2017-08-25
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 63
- Registration Number
- NCT03261921
Intraoperative Sedatives and Postoperative Deilirium
- Conditions
- Lower Extremity ProblemDeliriumPropofolDexmedetomidine
- Interventions
- First Posted Date
- 2017-08-16
- Last Posted Date
- 2022-07-11
- Lead Sponsor
- Seoul National University Bundang Hospital
- Target Recruit Count
- 748
- Registration Number
- NCT03251651
- Locations
- 🇰🇷
Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea, Republic of
Intranasal Sedation With Dexmedetomidine
- First Posted Date
- 2017-08-16
- Last Posted Date
- 2017-08-16
- Lead Sponsor
- University Medical Centre Ljubljana
- Target Recruit Count
- 40
- Registration Number
- NCT03251222
- Locations
- 🇸🇮
UMCLjubljana, CD of Anaesthesiology and Intensive Therapy, Ljubljana, Slovenia
SSEP Fluctuations Due to Dexmedetomidine During Posterior Spine Fusion
- First Posted Date
- 2017-08-02
- Last Posted Date
- 2017-08-03
- Lead Sponsor
- George Papanicolaou Hospital
- Target Recruit Count
- 25
- Registration Number
- NCT03236727
Effects of Comprehensive Intestinal Protection Strategy on Postoperative Intestinal Complications
- Conditions
- Intestinal ComplicationsLaparotomy
- Interventions
- Procedure: Ischemic preconditioningDrug: DexmedetomidineProcedure: Patient-controlled epidural analgesia
- First Posted Date
- 2017-07-13
- Last Posted Date
- 2017-07-13
- Lead Sponsor
- Nanfang Hospital, Southern Medical University
- Target Recruit Count
- 182
- Registration Number
- NCT03216759
Dexmedetomidine Infusion as an Analgesic Adjuvant During Laparoscopic Cholecystectomy
- Conditions
- Pain, Postoperative
- Interventions
- Drug: Normal Saline Flush, 0.9% Injectable Solution_#1Drug: Dexmedetomidine
- First Posted Date
- 2017-07-07
- Last Posted Date
- 2017-07-07
- Lead Sponsor
- Bogomolets National Medical University
- Target Recruit Count
- 60
- Registration Number
- NCT03211871
- Locations
- 🇺🇦
Kyiv Clinical City Hospital #1, Kyiv, Ukraine
Attenuation of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation With Single Dose of Dexmedetomidine in Hypertensive Patients.
- Conditions
- Stress Response During Laryngoscopy Intubation
- Interventions
- Drug: DexmedetomidineDrug: sterile saline
- First Posted Date
- 2017-06-29
- Last Posted Date
- 2020-04-07
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 70
- Registration Number
- NCT03204006
- Locations
- 🇪🇬
Assiut University Hospital, Assiut, Egypt
Dexmedetomidine Premedication in Children
- First Posted Date
- 2017-06-02
- Last Posted Date
- 2017-06-02
- Lead Sponsor
- Aydin Adnan Menderes University
- Target Recruit Count
- 100
- Registration Number
- NCT03174678
- Locations
- 🇹🇷
Sultan Keles, Aydın, Efeler, Turkey
Dexmedetomidine and Laparoscopic Surgery
- Conditions
- Anesthesia Complication
- Interventions
- Drug: Normal salineDrug: Dexmedetomidine
- First Posted Date
- 2017-06-01
- Last Posted Date
- 2020-08-21
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 60
- Registration Number
- NCT03172065
- Locations
- 🇪🇬
Assiut university, Assiut, Egypt
Drug Development Updates
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