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Dopamine

Generic Name
Dopamine
Drug Type
Small Molecule
Chemical Formula
C8H11NO2
CAS Number
51-61-6
Unique Ingredient Identifier
VTD58H1Z2X
Background

One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.

Indication

For the correction of hemodynamic imbalances present in the shock syndrome due to myocardial infarction, trauma, endotoxic septicemia, open-heart surgery, renal failure, and chronic cardiac decompensation as in congestive failure

Associated Conditions
Arrhythmia, Circulatory collapse and shock, Hypotension caused by Trauma, endotoxic septicemia, Open-heart Surgery, Renal Failure, chronic cardiac decompensation, Myocardial Infarction, Urine flow decreased caused by Trauma, endotoxic septicemia, Open-heart Surgery, Renal Failure, chronic cardiac decompensation, Myocardial Infarction, Decreased cardiac output caused by Trauma, endotoxic septicemia, Open-heart Surgery, Renal Failure, chronic cardiac decompensation, Myocardial Infarction
Clinical Trials
Related News

P2X7 Receptor, Inflammation and Neurodegenerative Diseases

Completed
Conditions
Neuro-Degenerative Disease
Interventions
First Posted Date
2019-04-17
Last Posted Date
2019-08-13
Lead Sponsor
University of Pisa
Target Recruit Count
50
Registration Number
NCT03918616
Locations
🇮🇹

University of Pisa, Pisa, Italy

The Comparative Effectiveness of Alprostadil,Sodium Ferulate and Dopamine in Pediatric Acute Kidney Injury

Phase 4
Conditions
Children AKI Patients
Interventions
Drug: Sodium Ferulate
First Posted Date
2019-03-27
Last Posted Date
2019-03-27
Lead Sponsor
Shengjing Hospital
Target Recruit Count
300
Registration Number
NCT03892447
Locations
🇨🇳

Shenjing Hospital, Shenyang, Liaoning, China

Dopamine and Norepinephrine Infusion With Restricted Hydration

Not Applicable
Completed
Conditions
Renal Function Test, Urine Output, Lactate Level
Interventions
First Posted Date
2018-12-19
Last Posted Date
2018-12-20
Lead Sponsor
Ain Shams University
Target Recruit Count
120
Registration Number
NCT03780686
Locations
🇪🇬

Ain Shams University, Cairo, Egypt

Study on Therapy of Non-invasive Prolactinoma

Not Applicable
Recruiting
Conditions
Prolactinoma
Interventions
Procedure: transsphenoidal surgery treatment
First Posted Date
2017-11-24
Last Posted Date
2017-11-24
Lead Sponsor
First Affiliated Hospital, Sun Yat-Sen University
Target Recruit Count
394
Registration Number
NCT03353025
Locations
🇨🇳

Sun Yat-sen 5010 program, Guangzhou, China

Effects of Dexmedetomidine and Dopamine on Renal Function After Major Surgery

Phase 4
Conditions
Renal Function
Interventions
First Posted Date
2017-05-31
Last Posted Date
2018-06-12
Lead Sponsor
Tao Zhang
Target Recruit Count
180
Registration Number
NCT03170739
Locations
🇨🇳

First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

Dopaminergic Modulation of Declarative Memory

Phase 4
Completed
Conditions
Parkinson's Disease
Interventions
First Posted Date
2017-05-12
Last Posted Date
2017-05-12
Lead Sponsor
I.R.C.C.S. Fondazione Santa Lucia
Target Recruit Count
40
Registration Number
NCT03151460
Locations
🇮🇹

Fondazione S. Lucia, Rome, Italy

The Effect of Norepinephrine Versus Dopamine in Renal Transplant Recipients on Postoperative Graft Function

Phase 2
Conditions
Renal Transplant
Interventions
First Posted Date
2017-04-11
Last Posted Date
2017-10-20
Lead Sponsor
Assiut University
Target Recruit Count
44
Registration Number
NCT03107858
Locations
🇪🇬

Assiut University Hospital, Assiut, Egypt

The Effect of Dopamine on Pulmonary Diffusion and Capillary Blood Volume During Exercise

Not Applicable
Active, not recruiting
Conditions
Health
Interventions
Drug: Placebos
Other: Rest
Other: Exercise - 60%
Other: Exercise - 85%
First Posted Date
2016-11-17
Last Posted Date
2025-05-07
Lead Sponsor
University of Alberta
Target Recruit Count
35
Registration Number
NCT02965963
Locations
🇨🇦

Clinical Physiology Research Laboratory, Edmonton, Alberta, Canada

Decision Support for Intraoperative Low Blood Pressure

Not Applicable
Completed
Conditions
Hypotension
Interventions
Procedure: Attending real-time decision support
Procedure: In-room real-time decision support
Procedure: Attending feedback emails
Procedure: In-room provider feedback emails
Device: Anesthesia Information Management System (AIMS)
Device: Perioperative Data Warehouse (PDW)
Procedure: General anesthesia
Device: Pager system
Procedure: Central neuraxial anesthesia
Procedure: Non-cardiac surgery
Drug: Ringer's lactate
Drug: Hydroxyethyl starch solutions
Drug: Packed Red Blood Cells
Drug: Albumin solutions
First Posted Date
2016-04-04
Last Posted Date
2019-05-16
Lead Sponsor
Vanderbilt University Medical Center
Target Recruit Count
22435
Registration Number
NCT02726620
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Target Hemodynamics and Brain Injury During General Anesthesia in the Elderly

Phase 2
Suspended
Conditions
Post-operative Cognitive Dysfunction
Interventions
Procedure: Hemodynamic target
Drug: Intravenous fluids
Procedure: Patient's positioning
Procedure: Reduction of depth of anesthesia
First Posted Date
2015-04-28
Last Posted Date
2018-04-13
Lead Sponsor
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Target Recruit Count
1812
Registration Number
NCT02428062
Locations
🇮🇹

Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico; Via F. Sforza 35, Milano, Italy

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