Dopamine

Generic Name
Dopamine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C8H11NO2
CAS Number
51-61-6
Unique Ingredient Identifier
VTD58H1Z2X
Background

One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.

Indication

For the correction of hemodynamic imbalances present in the shock syndrome due to myocardial infarction, trauma, endotoxic septicemia, open-heart surgery, renal failure, and chronic cardiac decompensation as in congestive failure

Associated Conditions
Arrhythmia, Circulatory collapse and shock, Hypotension caused by Trauma, endotoxic septicemia, Open-heart Surgery, Renal Failure, chronic cardiac decompensation, Myocardial Infarction, Urine flow decreased caused by Trauma, endotoxic septicemia, Open-heart Surgery, Renal Failure, chronic cardiac decompensation, Myocardial Infarction, Decreased cardiac output caused by Trauma, endotoxic septicemia, Open-heart Surgery, Renal Failure, chronic cardiac decompensation, Myocardial Infarction
Associated Therapies
-
Clinical Trials
Related News

The Effect of Dopamine on Pulmonary Diffusion and Capillary Blood Volume During Exercise

First Posted Date
2016-11-17
Last Posted Date
2024-12-04
Lead Sponsor
University of Alberta
Target Recruit Count
35
Registration Number
NCT02965963
Locations
🇨🇦

Clinical Physiology Research Laboratory, Edmonton, Alberta, Canada

Decision Support for Intraoperative Low Blood Pressure

Not Applicable
Completed
Conditions
Hypotension
Interventions
Procedure: Attending real-time decision support
Procedure: In-room real-time decision support
Procedure: Attending feedback emails
Procedure: In-room provider feedback emails
Device: Anesthesia Information Management System (AIMS)
Device: Perioperative Data Warehouse (PDW)
Procedure: General anesthesia
Device: Pager system
Procedure: Central neuraxial anesthesia
Procedure: Non-cardiac surgery
Drug: Propofol
Drug: Sevoflurane
Drug: Desflurane
Drug: Isoflurane
Drug: Ephedrine
Drug: Phenylephrine
Drug: Norepinephrine
Drug: Epinephrine
Drug: Dobutamine
Drug: Dopamine
Drug: Isoproterenol
Drug: Milrinone
Drug: Atropine
Drug: Glycopyrrolate
Drug: Vasopressin
Drug: Terlipressin
Drug: Sodium Chloride 0.9%
Drug: Ringer's lactate
Drug: Hydroxyethyl starch solutions
Drug: Fresh Frozen Plasma
Drug: Packed Red Blood Cells
Drug: Albumin solutions
Drug: Plasma-Lyte
Drug: Lidocaine
Drug: Bupivacaine
Drug: Levobupivacaine
Drug: Ropivacaine
Drug: Mepivacaine
Drug: Tetracaine
Drug: Prilocaine
Drug: Procaine
Drug: Chloroprocaine
Drug: Benzocaine
Drug: Articaine
First Posted Date
2016-04-04
Last Posted Date
2019-05-16
Lead Sponsor
Vanderbilt University Medical Center
Target Recruit Count
22435
Registration Number
NCT02726620
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Target Hemodynamics and Brain Injury During General Anesthesia in the Elderly

First Posted Date
2015-04-28
Last Posted Date
2018-04-13
Lead Sponsor
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Target Recruit Count
1812
Registration Number
NCT02428062
Locations
🇮🇹

Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico; Via F. Sforza 35, Milano, Italy

The Effect of Norepinephrine and Dopamine on Radial Forearm Free Flap Tissue Oxygen Pressure and Microdialysate Metabolite Measurements

First Posted Date
2014-09-16
Last Posted Date
2014-09-16
Lead Sponsor
Tampere University Hospital
Target Recruit Count
25
Registration Number
NCT02241083
Locations
🇫🇮

Tampere University Hospital, Tampere, P.O. Box 2000, Finland

Impact of Dopamine Infusion on Insulin Secretion in Healthy Subjects

Phase 1
Completed
Conditions
Hyperglycemia
Sepsis
Interventions
Drug: Dopamine
First Posted Date
2014-02-04
Last Posted Date
2016-08-09
Lead Sponsor
Albert Einstein College of Medicine
Target Recruit Count
15
Registration Number
NCT02053935
Locations
🇺🇸

Montefiore Medical Center of Albert Einstein College of Medicine, Bronx, New York, United States

Vasopressors for Cerebral Oxygenation

First Posted Date
2013-12-11
Last Posted Date
2013-12-11
Lead Sponsor
Samsung Medical Center
Target Recruit Count
50
Registration Number
NCT02009007
Locations
🇰🇷

Samsung medical center, Seoul, Korea, Republic of

Diuretics and Dopamine in Heart Failure With Preserved Ejection Fraction

Phase 4
Completed
Conditions
Heart Failure, Diastolic
Interventions
Drug: Furosemide
Drug: Dopamine
First Posted Date
2013-07-17
Last Posted Date
2018-08-16
Lead Sponsor
Johns Hopkins University
Target Recruit Count
90
Registration Number
NCT01901809
Locations
🇺🇸

Johns Hopkins Hospital, Baltimore, Maryland, United States

Renal Function During Laparoscopic Surgery

Not Applicable
Completed
Conditions
Intra Operative Fluid Management
Interventions
Drug: Dopamine
First Posted Date
2012-11-07
Last Posted Date
2012-11-07
Lead Sponsor
Catholic University of the Sacred Heart
Target Recruit Count
60
Registration Number
NCT01722630
Locations
🇮🇹

Catholic University of the sacred Heart, Rome, Italy

Dopamine Versus Dobutamine for Treatment of Arterial Hypotension in Term and Preterm Neonates

First Posted Date
2011-09-01
Last Posted Date
2016-04-06
Lead Sponsor
University of Ulm
Target Recruit Count
20
Registration Number
NCT01427686
Locations
🇩🇪

University Medical Center, Ulm University, Ulm, Baden-Württemberg, Germany

Study of Dopamine Versus Vasopressin for Treatment of Low Blood Pressure in Low Birth Weight Infants

Not Applicable
Completed
Conditions
Hypotension
Interventions
Drug: Arginine Vasopressin
Drug: Dopamine
First Posted Date
2011-03-18
Last Posted Date
2019-02-20
Lead Sponsor
Baylor College of Medicine
Target Recruit Count
70
Registration Number
NCT01318278
Locations
🇺🇸

Texas Children's Hospital, Houston, Texas, United States

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