Cefazolin
- Generic Name
- Cefazolin
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C14H14N8O4S3
- CAS Number
- 25953-19-9
- Unique Ingredient Identifier
- IHS69L0Y4T
- Background
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
- Indication
Mainly used to treat bacterial infections of the skin. It can also be used to treat moderately severe bacterial infections involving the lung, bone, joint, stomach, blood, heart valve, and urinary tract. It is clinically effective against infections caused by staphylococci and streptococci species of Gram positive bacteria. May be used for surgical prophylax...
- Associated Conditions
- Bacterial Septicemia caused by susceptible Bacterial Infections, Biliary tract infection bacterial caused by susceptible Bacterial Infections, Bone and Joint Infections caused by susceptible Bacterial Infections, Catheter-related Bloodstream Infection (CRBSI) NOS, Community Acquired Pneumonia (CAP), Endocarditis caused by susceptible Bacterial Infections, Genital infection caused by susceptible Bacterial Infections, Osteoarticular Infections, Postoperative Infections, Respiratory Tract Infection Bacterial caused by susceptible Bacterial Infections, Skin and Soft Tissue Infections (SSTIs), Skin and Subcutaneous Tissue Infection caused by susceptible Bacterial Infections, Susceptible infections, Urinary Tract Infection caused by susceptible Bacterial Infections, Perioperative infection, Susceptible Bacterial Infections
- Associated Therapies
- Antibiotic pre-surgical prophylaxis
Antibiotic Prophylaxis to Prevent Obesity-Related Induction Complications in Nulliparae at Term
- Conditions
- Interventions
- First Posted Date
- 2019-01-11
- Last Posted Date
- 2024-04-19
- Lead Sponsor
- University of Oklahoma
- Target Recruit Count
- 186
- Registration Number
- NCT03801252
- Locations
- 🇺🇸
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States
Defining the Optimal Duration of Treatment for "Low-Risk" Peritoneal Dialysis-Related Peritonitis
- First Posted Date
- 2018-09-18
- Last Posted Date
- 2019-11-13
- Lead Sponsor
- Chinese University of Hong Kong
- Registration Number
- NCT03675854
- Locations
- 🇭🇰
Department of Medicine & Therapeutics, Prince of Wales Hospital, Shatin, Hong Kong
Safety and Therapeutic Drug Monitoring of Cefazolin in Continuous Renal Replacement Therapy
- First Posted Date
- 2018-09-14
- Last Posted Date
- 2020-10-19
- Lead Sponsor
- Drexel University
- Target Recruit Count
- 20
- Registration Number
- NCT03672149
- Locations
- 🇺🇸
St. Christopher's Hospital for Children, Philadelphia, Pennsylvania, United States
Antibiotic Prophylaxis in Clean Surgery. Impact on Surgical Site Infection
- First Posted Date
- 2018-07-23
- Last Posted Date
- 2019-09-04
- Lead Sponsor
- University of Rwanda
- Target Recruit Count
- 138
- Registration Number
- NCT03595852
- Locations
- 🇷🇼
Kigali University Teaching Hospital (Chuk), Kigali, Rwanda
Bowel Preparation in Elective Pediatric Colorectal Surgery
- Conditions
- Interventions
- First Posted Date
- 2018-07-20
- Last Posted Date
- 2021-12-09
- Lead Sponsor
- McMaster University
- Target Recruit Count
- 81
- Registration Number
- NCT03593252
Does Antibiotic Prophylaxis Reduce Wound Complications After Vulvar Excision of Premalignant Lesions
- Conditions
- Interventions
- First Posted Date
- 2018-07-06
- Last Posted Date
- 2022-11-21
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 50
- Registration Number
- NCT03578965
- Locations
- 🇺🇸
Washington University School of Medicine, Saint Louis, Missouri, United States
The Effectiveness of Vancomycin in Comarison With Cefazolin in Prevention of SSI After Craniotomy
- Conditions
- Interventions
- First Posted Date
- 2018-03-15
- Last Posted Date
- 2018-03-15
- Lead Sponsor
- Isfahan University of Medical Sciences
- Target Recruit Count
- 126
- Registration Number
- NCT03466645
- Locations
- 🇮🇷
Isfahan university of medical science., Isfahan, Iran, Islamic Republic of
Preoperative Antibiotics for Carpal Tunnel Release Surgery
- Conditions
- Interventions
- First Posted Date
- 2018-02-14
- Last Posted Date
- 2021-11-10
- Lead Sponsor
- WellSpan Health
- Target Recruit Count
- 184
- Registration Number
- NCT03432858
- Locations
- 🇺🇸
WellSpan Surgery and Rehab Hospital, York, Pennsylvania, United States
Prevention of Infections in Cardiac Surgery (PICS) Prevena Study
- Conditions
- Interventions
- First Posted Date
- 2018-01-18
- Last Posted Date
- 2024-11-25
- Lead Sponsor
- Population Health Research Institute
- Target Recruit Count
- 4107
- Registration Number
- NCT03402945
- Locations
- 🇨🇦
Hamilton General Hospital, Hamilton, Ontario, Canada
🇨🇦London Health Sciences Centre & Lawson Health Research Institute, London, Ontario, Canada
Antibiotic Prophylaxis in Patients Undergoing Elective TKA- Multi-center Trial
- Conditions
- Interventions
- First Posted Date
- 2017-09-14
- Last Posted Date
- 2024-11-27
- Lead Sponsor
- Duke University
- Target Recruit Count
- 8000
- Registration Number
- NCT03283878
- Locations
- 🇺🇸
University of California, San Francisco, San Francisco, California, United States
🇺🇸Emory University, Atlanta, Georgia, United States
🇺🇸University of Maryland St. Joseph Medical Center & Orthopedic Associates, Towson, Maryland, United States
Drug Development Updates
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