VANDERBILT UNIVERSITY MEDICAL CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private, Subsidiary

Established: 1925-01-01

Employees: 10K

Market Cap: -

Website: http://www.vumc.org

Clinical Trials

Moderate Dose Hydroxyurea for Secondary Stroke Prevention in Children With Sickle Cell Disease in Sub-Saharan Africa

Phase 3

Completed

Conditions: Sickle Cell Disease
Sickle Cell Anemia
Stroke

Interventions: Drug: Moderate Dose Hydroxyurea
Drug: Low Dose Hydroxyurea

First Posted Date: 2016-02-05

Last Posted Date: 2022-01-19

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 120

Registration Number: NCT02675790

Locations: 🇳🇬
Murtala Muhammad Specialist Hospital, Kano, Nigeria
🇳🇬
Aminu Kano Teaching Hospital, Kano, Nigeria

Pediatric Acute Kidney Injury (AKI) Retrospective, Real-Time and Repository Research

Not Applicable

Completed

Conditions: Renal Injury
Kidney Disease
Acute Kidney Injury

Interventions: Other: AKI Risk Notification

First Posted Date: 2016-01-21

Last Posted Date: 2019-04-03

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 12108

Registration Number: NCT02660931

Locations: 🇺🇸
Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee, United States

Serial, Non-invasive Analysis of Exhaled Breath Condensate in Ventilated Trauma Patients

Not Applicable

Terminated

Conditions: Ventilator Associated Pneumonia (VAP)

Interventions: Procedure: molecular analysis of exhaled breath condensate
Procedure: molecular analysis of mini-bronchoalveolar lavage (BAL) aspirate
Procedure: molecular analysis of bronchoalveolar lavage (BAL) aspirate

First Posted Date: 2016-01-11

Last Posted Date: 2022-08-04

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 110

Registration Number: NCT02652247

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

Natriuretic Peptides and Metabolic Risk in Obesity

Early Phase 1

Withdrawn

Conditions: Obesity
Hyperinsulinemia

Interventions: Drug: Insulin
Other: Saline
Drug: Nesiritide

First Posted Date: 2015-12-30

Last Posted Date: 2017-11-06

Lead Sponsor: Vanderbilt University Medical Center

Registration Number: NCT02642523

Increasing Minority Participation in Clinical Trials

Not Applicable

Completed

Conditions: Clinical Trial

Interventions: Procedure: Video viewing group

First Posted Date: 2015-11-09

Last Posted Date: 2017-09-11

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 63

Registration Number: NCT02600533

Locations: 🇺🇸
Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States

Blood Pressure Lowering Effects of Angiotensin-(1-7) in Primary Autonomic Failure

Early Phase 1

Terminated

Conditions: Autonomic Nervous System Disorders
Pure Autonomic Failure
Shy-Drager Syndrome
Orthostatic Hypotension, Dysautonomic

Interventions: Drug: Angiotensin-(1-7)
Drug: Saline

First Posted Date: 2015-10-29

Last Posted Date: 2021-01-12

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 7

Registration Number: NCT02591173

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

Trial Evaluating Postop Pain and Muscle Strength Among Regional Anesthesia Techniques for Ambulatory ACL Reconstruction

Not Applicable

Completed

Conditions: Rupture of Anterior Cruciate Ligament
Tear of Anterior Cruciate Ligament

Interventions: Drug: Mepivacaine
Procedure: adductor canal continuous nerve catheter
Procedure: adductor canal nerve block
Drug: Normal Saline as bolus followed by bupivacaine
Drug: ropivacaine and dexamethasone
Drug: Propofol
Drug: Fentanyl

First Posted Date: 2015-10-22

Last Posted Date: 2019-12-11

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 59

Registration Number: NCT02584452

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

Comparison of Mask Ventilation Techniques in Patients Requiring General Anesthesia

Not Applicable

Completed

Conditions: Apnea

Interventions: Procedure: V-E mask ventilation for one minute
Procedure: C-E mask ventilation for one minute

First Posted Date: 2015-10-20

Last Posted Date: 2017-07-11

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 104

Registration Number: NCT02580526

Locations: 🇺🇸
Vanderbilt University, Nashville, Tennessee, United States

Primary Prevention of Stroke in Children With SCD in Sub-Saharan Africa II

Phase 3

Completed

Conditions: Stroke
Sickle Cell Disease

Interventions: Drug: Hydroxyurea (Moderate Dose)
Drug: Hydroxyurea (Low Dose)

First Posted Date: 2015-09-25

Last Posted Date: 2020-08-03

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 440

Registration Number: NCT02560935

Locations: 🇳🇬
Barau Dikko Teaching Hospital/Kaduna State University, Kaduna, Nigeria
🇳🇬
Murtala Muhammad Specialist Hospital, Kano, Nigeria
🇳🇬
Aminu Kano Teaching Hospital, Kano, Nigeria

Role of the Foregut in Nutrient Metabolism in Lean and Obese Humans

Phase 1

Completed

Conditions: Obesity

Interventions: Other: placebo
Drug: benzocaine

First Posted Date: 2015-09-01

Last Posted Date: 2022-12-09

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 27

Registration Number: NCT02537314

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

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