Zaleplon

Generic Name
Zaleplon
Brand Names
Sonata
Drug Type
Small Molecule
Chemical Formula
C17H15N5O
CAS Number
151319-34-5
Unique Ingredient Identifier
S62U433RMH
Background

Zaleplon is a sedative/hypnotic, mainly used for insomnia. It is known as a nonbenzodiazepine hypnotic. Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of the benzodiazepines. Zaleplon is a schedule IV drug in the United States.

Indication

For the treatment of short-term treatment of insomnia in adults.

Associated Conditions
Insomnia
Associated Therapies
-

Zaleplon in HIV Patients With Depression

Phase 2
Completed
Conditions
Interventions
First Posted Date
2018-04-05
Last Posted Date
2018-10-16
Lead Sponsor
University of Pennsylvania
Target Recruit Count
20
Registration Number
NCT03489304
Locations
🇺🇸

Mood & Anxiety Disorders Research and Treatment Program, Philadelphia, Pennsylvania, United States

Cerebral MRI During Sleep

Completed
Conditions
First Posted Date
2017-10-09
Last Posted Date
2019-03-14
Lead Sponsor
University of California, San Diego
Target Recruit Count
11
Registration Number
NCT03304652
Locations
🇺🇸

UC San Diego, San Diego, California, United States

Pharmacovigilance in Gerontopsychiatric Patients

Phase 3
Terminated
Conditions
Interventions
Drug: Phenobarbital
Drug: Phenytoin
Drug: Carbamazepine
Drug: Oxcarbazepine
Drug: Valproic Acid
Drug: Lamotrigine
Drug: Topiramate
Drug: Gabapentin
Drug: Levetiracetam
Drug: Pregabalin
Drug: Lacosamide
Drug: Clonazepam
Drug: Biperiden
Drug: Levomepromazine
Drug: Fluphenazine
Drug: Perphenazine
Drug: Perazine
Drug: Thioridazine
Drug: Haloperidol
Drug: Melperone
Drug: Pipamperone
Drug: Bromperidol
Drug: Benperidol
Drug: Sertindole
Drug: Ziprasidone
Drug: Flupentixol
Drug: Chlorprothixene
Drug: Zuclopenthixol
Drug: Fluspirilene
Drug: Pimozide
Drug: Clozapine
Drug: Olanzapine
Drug: Quetiapine
Drug: Sulpiride
Drug: Tiapride
Drug: Amisulpride
Drug: Prothipendyl
Drug: Risperidone
Drug: Aripiprazole
Drug: Paliperidone
Drug: Diazepam
Drug: Oxazepam
Drug: Lorazepam
Drug: Bromazepam
Drug: Clobazam
Drug: Alprazolam
Drug: Hydroxyzine
Drug: Buspirone
Drug: Chloral Hydrate
Drug: Flurazepam
Drug: Nitrazepam
Drug: Triazolam
Drug: Lormetazepam
Drug: Temazepam
Drug: Midazolam
Drug: Brotizolam
Drug: Zopiclone
Drug: Zolpidem
Drug: Zaleplon
Drug: Melatonin
Drug: Clomethiazole
Drug: Diphenhydramine
Drug: Promethazine
Drug: Imipramine
Drug: Clomipramine
Drug: Opipramol
Drug: Trimipramine
Drug: Amitriptyline
Drug: Nortriptyline
Drug: Doxepin
Drug: Maprotiline
Drug: Amitriptyline oxide
Drug: Fluoxetine
Drug: Citalopram
Drug: Paroxetine
Drug: Sertraline
Drug: Fluvoxamine
Drug: Escitalopram
Drug: Tranylcypromine
Drug: Moclobemide
Drug: Mianserin
Drug: Trazodone
Drug: Mirtazapine
Drug: Bupropion
Drug: Venlafaxine
Drug: Reboxetine
Drug: Duloxetine
Drug: Agomelatine
Drug: Pyritinol
Drug: Piracetam
Drug: Donepezil
Drug: Rivastigmine
Drug: Galantamine
Drug: Memantine
Drug: Nicergoline
Drug: Acamprosate
Drug: Lithium
First Posted Date
2015-03-02
Last Posted Date
2018-02-28
Lead Sponsor
Hannover Medical School
Target Recruit Count
407
Registration Number
NCT02374567
Locations
🇩🇪

Bezirkskrankenhaus Augsburg, Augsburg, Germany

🇩🇪

Krankenhaus Hedwigshöhe, Berlin, Germany

🇩🇪

Hannover Medical School, Hannover, Germany

and more 2 locations

Hypnotic Medications and Memory: Effect of Drug Exposure During the Night

First Posted Date
2010-07-09
Last Posted Date
2014-08-26
Lead Sponsor
St. Luke's Hospital, Chesterfield, Missouri
Target Recruit Count
26
Registration Number
NCT01159652
Locations
🇺🇸

St. Luke's Hospital Sleep Medicine and Research Center, Chesterfield, Missouri, United States

Bioequivalency Study of Zaleplon 10 mg Capsules Under Fed Conditions

Not Applicable
Completed
Conditions
First Posted Date
2008-06-10
Last Posted Date
2018-01-23
Lead Sponsor
Roxane Laboratories
Target Recruit Count
40
Registration Number
NCT00694317
Locations
🇺🇸

Novum Pharmaceutical Research Services, Houston, Texas, United States

Bioequivalency Study of Zaleplon 10 mg Capsules Under Fasting Conditions

Not Applicable
Completed
Conditions
First Posted Date
2008-06-10
Last Posted Date
2018-01-23
Lead Sponsor
Roxane Laboratories
Target Recruit Count
39
Registration Number
NCT00694187
Locations
🇺🇸

Novum Pharmaceutical Research Services, Houston, Texas, United States

© Copyright 2024. All Rights Reserved by MedPath