Olanzapine

Generic Name
Olanzapine
Brand Names
Lybalvi, Olazax, Symbyax, Zalasta, Zypadhera, Zyprexa, Olanzapine Glenmark Europe, Olanzapine Apotex, Olanzapine Teva, Olazax Disperzi, Olanzapine Mylan, Zyprexa Velotab, Olanzapine Glenmark
Drug Type
Small Molecule
Chemical Formula
C17H20N4S
CAS Number
132539-06-1
Unique Ingredient Identifier
N7U69T4SZR
Background

Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resemb...

Indication

Olanzapine was initially used orally and intramuscularly for the chronic treatment of schizophrenia in patients over 13 years old and other psychiatric disorders such as bipolar I disorder including mixed or manic episodes.
...

Associated Conditions
Acute Agitation, Bipolar 1 Disorder, Bipolar Disorder With Manic or Mixed Episodes, Delirium, Delusional Parasitosis, Depressive Episodes, Gilles de la Tourette's Syndrome, Major depressive disorder, recurrent episode, Mixed manic depressive episode, Post Traumatic Stress Disorder (PTSD), Psychosis, Schizophrenia, Acute Manic episode
Associated Therapies
-
Clinical Trials
Related News

Pharmacovigilance in Gerontopsychiatric Patients

Phase 3
Terminated
Conditions
Dementia
Depression
Schizophrenia
Psychosomatic Disorders
Anxiety Disorders
Interventions
Drug: Phenobarbital
Drug: Phenytoin
Drug: Carbamazepine
Drug: Oxcarbazepine
Drug: Valproic Acid
Drug: Lamotrigine
Drug: Topiramate
Drug: Gabapentin
Drug: Levetiracetam
Drug: Pregabalin
Drug: Lacosamide
Drug: Clonazepam
Drug: Biperiden
Drug: Levomepromazine
Drug: Fluphenazine
Drug: Perphenazine
Drug: Perazine
Drug: Thioridazine
Drug: Haloperidol
Drug: Melperone
Drug: Pipamperone
Drug: Bromperidol
Drug: Benperidol
Drug: Sertindole
Drug: Ziprasidone
Drug: Flupentixol
Drug: Chlorprothixene
Drug: Zuclopenthixol
Drug: Fluspirilene
Drug: Pimozide
Drug: Clozapine
Drug: Olanzapine
Drug: Quetiapine
Drug: Sulpiride
Drug: Tiapride
Drug: Amisulpride
Drug: Prothipendyl
Drug: Risperidone
Drug: Aripiprazole
Drug: Paliperidone
Drug: Diazepam
Drug: Oxazepam
Drug: Lorazepam
Drug: Bromazepam
Drug: Clobazam
Drug: Alprazolam
Drug: Hydroxyzine
Drug: Buspirone
Drug: Chloral Hydrate
Drug: Flurazepam
Drug: Nitrazepam
Drug: Triazolam
Drug: Lormetazepam
Drug: Temazepam
Drug: Midazolam
Drug: Brotizolam
Drug: Zopiclone
Drug: Zolpidem
Drug: Zaleplon
Drug: Melatonin
Drug: Clomethiazole
Drug: Diphenhydramine
Drug: Promethazine
Drug: Imipramine
Drug: Clomipramine
Drug: Opipramol
Drug: Trimipramine
Drug: Amitriptyline
Drug: Nortriptyline
Drug: Doxepin
Drug: Maprotiline
Drug: Amitriptyline oxide
Drug: Fluoxetine
Drug: Citalopram
Drug: Paroxetine
Drug: Sertraline
Drug: Fluvoxamine
Drug: Escitalopram
Drug: Tranylcypromine
Drug: Moclobemide
Drug: Mianserin
Drug: Trazodone
Drug: Mirtazapine
Drug: Bupropion
Drug: Venlafaxine
Drug: Reboxetine
Drug: Duloxetine
Drug: Agomelatine
Drug: Pyritinol
Drug: Piracetam
Drug: Donepezil
Drug: Rivastigmine
Drug: Galantamine
Drug: Memantine
Drug: Nicergoline
Drug: Acamprosate
Drug: Lithium
First Posted Date
2015-03-02
Last Posted Date
2018-02-28
Lead Sponsor
Hannover Medical School
Target Recruit Count
407
Registration Number
NCT02374567
Locations
🇩🇪

Bezirkskrankenhaus Augsburg, Augsburg, Germany

🇩🇪

Krankenhaus Hedwigshöhe, Berlin, Germany

🇩🇪

Hannover Medical School, Hannover, Germany

and more 2 locations

Evaluation of the Necessity of Long-term Pharmacological Treatment With Antipsychotics in Schizophrenic Patients

First Posted Date
2014-12-04
Last Posted Date
2018-10-11
Lead Sponsor
Technical University of Munich
Target Recruit Count
21
Registration Number
NCT02307396
Locations
🇩🇪

Psychiatrische Klinik und Poliklinik fuer Psychiatrie und Psychotherapie der Technischen Universitaet Muenchen am Klinikum rechts der Isar, Munich, Bavaria, Germany

Olanzapine Against Delayed Nausea and Vomiting in Women Receiving Carboplatin Plus Paclitaxel

First Posted Date
2014-11-14
Last Posted Date
2014-11-14
Lead Sponsor
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Target Recruit Count
81
Registration Number
NCT02290470
Locations
🇮🇹

Istituto Nazionale dei Tumori, Milan, Italy

Olanzapine Versus Lithium in the Treatment of Acute Depression in Patients With Bipolar II or Bipolar Not Otherwise Specified(OL Study)

Phase 4
Completed
Conditions
Bipolar Disorder
Interventions
Drug: olanzapine
Drug: lithium
First Posted Date
2014-11-10
Last Posted Date
2019-12-05
Lead Sponsor
Tadashi Hasegawa
Target Recruit Count
50
Registration Number
NCT02287259
Locations
🇯🇵

Chiba University Hospital, Chiba-shi, Japan

A Randomized Double-blind Trial With 6 Antipsychotic Drugs for Schizophrenia

First Posted Date
2014-07-17
Last Posted Date
2016-07-12
Lead Sponsor
Beijing HuiLongGuan Hospital
Target Recruit Count
550
Registration Number
NCT02192723
Locations
🇨🇳

Beijing HuiLongGuan Hospital, Beijing, China

Antipsychotic to Treat Psychosis Syndrome

First Posted Date
2014-05-14
Last Posted Date
2014-05-14
Lead Sponsor
Central South University
Target Recruit Count
300
Registration Number
NCT02137616
Locations
🇨🇳

the Second Xiangya Hospital, Changsha, Hunan, China

Olanzapine for Prevention of Chemotherapy-induced Nausea and Vomiting in Children: A Multi-Centre Feasibility Study

Phase 2
Completed
Conditions
Chemotherapy-induced Nausea and Vomiting
Interventions
Drug: Olanzapine
First Posted Date
2014-05-02
Last Posted Date
2020-04-07
Lead Sponsor
The Hospital for Sick Children
Target Recruit Count
15
Registration Number
NCT02129478
Locations
🇨🇦

Children's Hospital, London Health Sciences Centre, London, Ontario, Canada

🇨🇦

The Hospital for Sick Children, Toronto, Ontario, Canada

🇨🇦

Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada

Antiemetic Therapy With or Without Olanzapine in Preventing Chemotherapy-Induced Nausea and Vomiting in Patients With Cancer Receiving Highly Emetogenic Chemotherapy

First Posted Date
2014-04-17
Last Posted Date
2020-05-07
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
401
Registration Number
NCT02116530
Locations
🇺🇸

Southwest Oncology PC, Durango, Colorado, United States

🇺🇸

Saint Luke's Mountain States Tumor Institute - Nampa, Nampa, Idaho, United States

🇺🇸

Illinois CancerCare Galesburg, Galesburg, Illinois, United States

and more 174 locations

Pilot Study of Olanzapine and Aprepitant to Prevent Nausea and Vomiting in Children Receiving Chemotherapy

First Posted Date
2014-03-27
Last Posted Date
2017-03-30
Lead Sponsor
Indiana University
Target Recruit Count
15
Registration Number
NCT02097823
Locations
🇺🇸

Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana, United States

A Four-week Clinical Trial Investigating Efficacy and Safety of Cannabidiol as a Treatment for Acutely Ill Schizophrenic Patients

First Posted Date
2014-03-14
Last Posted Date
2024-01-25
Lead Sponsor
Central Institute of Mental Health, Mannheim
Target Recruit Count
150
Registration Number
NCT02088060
Locations
🇩🇪

Department of General Psychiatry, Heidelberg University, Heidelberg, BW, Germany

🇩🇪

Dept. of Psychiatry and Psychotherapy, Technical University Munich, Munich, BY, Germany

🇩🇪

Dep. of Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, BW, Germany

and more 3 locations
© Copyright 2024. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy