Buspirone

Generic Name
Buspirone
Brand Names
Buspar
Drug Type
Small Molecule
Chemical Formula
C21H31N5O2
CAS Number
36505-84-7
Unique Ingredient Identifier
TK65WKS8HL
Background

Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. Belonging to the azaspirodecanedione drug class, buspirone is a serotonin 5-HT receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and other sedative/anxiolytic drugs. Unlike many drugs used to treat anxiety, buspiro...

Indication

Indicated for the management of anxiety disorders or the short-term relief of the symptoms of anxiety.

Associated Conditions
Anxiety Disorders, Depression
Associated Therapies
-
Clinical Trials
Related News

Improving Driving in Young People With Autism Spectrum Disorders

Phase 4
Completed
Conditions
Autism Spectrum Disorder
Interventions
Drug: Buspirone
First Posted Date
2018-05-29
Last Posted Date
2021-03-18
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
26
Registration Number
NCT03538431
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Buspirone Plus Omeprazole for Functional Dyspepsia

Phase 4
Completed
Conditions
Dyspepsia
Interventions
Drug: Placebo Oral Tablet
Drug: Buspirone
First Posted Date
2018-02-23
Last Posted Date
2018-02-23
Lead Sponsor
Isfahan University of Medical Sciences
Target Recruit Count
70
Registration Number
NCT03444831

A Pilot Study of Buspirone for the Treatment of Anxiety in Youth With Autism Spectrum Disorders

Phase 2
Not yet recruiting
Conditions
Autism Spectrum Disorder
Anxiety
Interventions
Drug: Buspirone
First Posted Date
2018-02-13
Last Posted Date
2024-07-10
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
15
Registration Number
NCT03432065
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Buspirone in Parkinson's Disease

Phase 2
Completed
Conditions
Parkinson Disease
Anxiety
Interventions
Drug: Placebo
Drug: Buspirone
First Posted Date
2016-06-17
Last Posted Date
2020-01-02
Lead Sponsor
University of Rochester
Target Recruit Count
21
Registration Number
NCT02803749
Locations
🇺🇸

University of Rochester Medical Center, Rochester, New York, United States

Buspirone for Functional Dysphagia

First Posted Date
2016-02-04
Last Posted Date
2018-08-10
Lead Sponsor
The Cleveland Clinic
Target Recruit Count
10
Registration Number
NCT02674412

Buspirone Treatment of Iatrogenic Dyskinesias in Advanced Parkinson' Disease

Phase 3
Completed
Conditions
Parkinson
Interventions
Drug: Placebo
Drug: Buspirone
First Posted Date
2015-11-30
Last Posted Date
2023-04-12
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Target Recruit Count
99
Registration Number
NCT02617017
Locations
🇫🇷

Henri Mondor Hospital, Creteil, France

Buspirone, in Combination With Amantadine, for the Treatment of Levodopa-induced Dyskinesia

First Posted Date
2015-10-28
Last Posted Date
2021-03-05
Lead Sponsor
Oregon Health and Science University
Target Recruit Count
6
Registration Number
NCT02589340
Locations
🇺🇸

VA Portland Health Care System, Portland, Oregon, United States

Mechanistic Investigation Of Intestinal Cytochrome p450 3A4 Following Roux-en-Y Surgery And Its Effect on Plasma Concentrations of Buspirone

First Posted Date
2015-06-29
Last Posted Date
2018-08-24
Lead Sponsor
North Dakota State University
Target Recruit Count
12
Registration Number
NCT02483598

Role of Enhancing Serotonin Receptors Activity for Sleep Apnea Treatment in Patients With SCI

First Posted Date
2015-06-01
Last Posted Date
2021-06-14
Lead Sponsor
VA Office of Research and Development
Target Recruit Count
15
Registration Number
NCT02458469
Locations
🇺🇸

John D. Dingell VA Medical Center, Detroit, MI, Detroit, Michigan, United States

Pharmacovigilance in Gerontopsychiatric Patients

Phase 3
Terminated
Conditions
Dementia
Depression
Schizophrenia
Psychosomatic Disorders
Anxiety Disorders
Interventions
Drug: Phenobarbital
Drug: Phenytoin
Drug: Carbamazepine
Drug: Oxcarbazepine
Drug: Valproic Acid
Drug: Lamotrigine
Drug: Topiramate
Drug: Gabapentin
Drug: Levetiracetam
Drug: Pregabalin
Drug: Lacosamide
Drug: Clonazepam
Drug: Biperiden
Drug: Levomepromazine
Drug: Fluphenazine
Drug: Perphenazine
Drug: Perazine
Drug: Thioridazine
Drug: Haloperidol
Drug: Melperone
Drug: Pipamperone
Drug: Bromperidol
Drug: Benperidol
Drug: Sertindole
Drug: Ziprasidone
Drug: Flupentixol
Drug: Chlorprothixene
Drug: Zuclopenthixol
Drug: Fluspirilene
Drug: Pimozide
Drug: Clozapine
Drug: Olanzapine
Drug: Quetiapine
Drug: Sulpiride
Drug: Tiapride
Drug: Amisulpride
Drug: Prothipendyl
Drug: Risperidone
Drug: Aripiprazole
Drug: Paliperidone
Drug: Diazepam
Drug: Oxazepam
Drug: Lorazepam
Drug: Bromazepam
Drug: Clobazam
Drug: Alprazolam
Drug: Hydroxyzine
Drug: Buspirone
Drug: Chloral Hydrate
Drug: Flurazepam
Drug: Nitrazepam
Drug: Triazolam
Drug: Lormetazepam
Drug: Temazepam
Drug: Midazolam
Drug: Brotizolam
Drug: Zopiclone
Drug: Zolpidem
Drug: Zaleplon
Drug: Melatonin
Drug: Clomethiazole
Drug: Diphenhydramine
Drug: Promethazine
Drug: Imipramine
Drug: Clomipramine
Drug: Opipramol
Drug: Trimipramine
Drug: Amitriptyline
Drug: Nortriptyline
Drug: Doxepin
Drug: Maprotiline
Drug: Amitriptyline oxide
Drug: Fluoxetine
Drug: Citalopram
Drug: Paroxetine
Drug: Sertraline
Drug: Fluvoxamine
Drug: Escitalopram
Drug: Tranylcypromine
Drug: Moclobemide
Drug: Mianserin
Drug: Trazodone
Drug: Mirtazapine
Drug: Bupropion
Drug: Venlafaxine
Drug: Reboxetine
Drug: Duloxetine
Drug: Agomelatine
Drug: Pyritinol
Drug: Piracetam
Drug: Donepezil
Drug: Rivastigmine
Drug: Galantamine
Drug: Memantine
Drug: Nicergoline
Drug: Acamprosate
Drug: Lithium
First Posted Date
2015-03-02
Last Posted Date
2018-02-28
Lead Sponsor
Hannover Medical School
Target Recruit Count
407
Registration Number
NCT02374567
Locations
🇩🇪

Bezirkskrankenhaus Augsburg, Augsburg, Germany

🇩🇪

Krankenhaus Hedwigshöhe, Berlin, Germany

🇩🇪

Hannover Medical School, Hannover, Germany

and more 2 locations
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