MedPath

Fluphenazine

Generic Name
Fluphenazine
Brand Names
Modecate
Drug Type
Small Molecule
Chemical Formula
C22H26F3N3OS
CAS Number
69-23-8
Unique Ingredient Identifier
S79426A41Z
Background

A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.

Indication

For management of manifestations of psychotic disorders.

Associated Conditions
Chorea, Depression, Gilles de la Tourette's Syndrome, Psychosis
Associated Therapies
Sedation

Pharmacovigilance in Gerontopsychiatric Patients

Phase 3
Terminated
Conditions
Dementia
Depression
Schizophrenia
Psychosomatic Disorders
Anxiety Disorders
Interventions
First Posted Date
2015-03-02
Last Posted Date
2018-02-28
Lead Sponsor
Hannover Medical School
Target Recruit Count
407
Registration Number
NCT02374567
Locations
🇩🇪

Bezirkskrankenhaus Augsburg, Augsburg, Germany

🇩🇪

Krankenhaus Hedwigshöhe, Berlin, Germany

🇩🇪

Hannover Medical School, Hannover, Germany

and more 2 locations

Evaluation of the Necessity of Long-term Pharmacological Treatment With Antipsychotics in Schizophrenic Patients

First Posted Date
2014-12-04
Last Posted Date
2018-10-11
Lead Sponsor
Technical University of Munich
Target Recruit Count
21
Registration Number
NCT02307396
Locations
🇩🇪

Psychiatrische Klinik und Poliklinik fuer Psychiatrie und Psychotherapie der Technischen Universitaet Muenchen am Klinikum rechts der Isar, Munich, Bavaria, Germany

D1 and D2 Dopamine Receptors in Gambling and Amphetamine Reinforcement

Phase 2
Completed
Conditions
Pathological Gambling
Interventions
Drug: Placebo
Behavioral: Slot Machine
First Posted Date
2014-07-30
Last Posted Date
2016-04-25
Lead Sponsor
Centre for Addiction and Mental Health
Target Recruit Count
60
Registration Number
NCT02203786
Locations
🇨🇦

Centre for Addiction and Mental Health, Toronto, Ontario, Canada

Fluphenazine Hydrochloride for Psoriasis

Phase 2
Completed
Conditions
Psoriasis
Interventions
Drug: Placebo
First Posted Date
2009-06-29
Last Posted Date
2017-03-31
Lead Sponsor
Tufts Medical Center
Target Recruit Count
15
Registration Number
NCT00929578
Locations
🇺🇸

Tufts Medical Center, Department of Dermatology, Boston, Massachusetts, United States

🇺🇸

Robert Wood Johnson Medical School, Psoriasis Center of Excellence, New Brunswick, New Jersey, United States

Study of Fluphenazine in Relapsed or Relapsed-and-Refractory Multiple Myeloma

Phase 1
Conditions
Multiple Myeloma
First Posted Date
2009-01-13
Last Posted Date
2009-01-13
Lead Sponsor
Immune Control
Target Recruit Count
30
Registration Number
NCT00821301
Locations
🇺🇸

University of Pittsburgh Cancer Institute Hillman Cancer Center, Pittsburgh, Pennsylvania, United States

🇺🇸

Cancer Therapy and Research Center at the UT Health Sciences Center at San Antonio, San Antonio, Texas, United States

🇺🇸

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

Fluphenazine Decanoate for Psoriasis

Phase 2
Terminated
Conditions
Psoriasis
Interventions
First Posted Date
2006-07-25
Last Posted Date
2010-12-22
Lead Sponsor
Tufts Medical Center
Target Recruit Count
10
Registration Number
NCT00356200
Locations
🇺🇸

Tufts-New England Medical Center, Boston, Massachusetts, United States

Fluphenazine in Treating Patients With Refractory Advanced Multiple Myeloma

Phase 1
Completed
Conditions
Multiple Myeloma and Plasma Cell Neoplasm
First Posted Date
2006-06-12
Last Posted Date
2013-11-06
Lead Sponsor
Immune Control
Target Recruit Count
30
Registration Number
NCT00335647
Locations
🇺🇸

Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

🇺🇸

Long Island Jewish Medical Center, New Hyde Park, New York, United States

🇺🇸

Hackensack University Medical Center Cancer Center, Hackensack, New Jersey, United States

New Antipsychotic Strategies: Quetiapine and Risperidone vs. Fluphenazine in Treatment Resistant Schizophrenia

Phase 3
Completed
Conditions
Schizophrenia
First Posted Date
2005-09-12
Last Posted Date
2019-08-19
Lead Sponsor
University of Maryland, Baltimore
Target Recruit Count
150
Registration Number
NCT00161018
Locations
🇺🇸

Maryland Psychiatric Research Center, Catonsville, Maryland, United States

CATIE- Schizophrenia Trial

Phase 4
Completed
Conditions
Schizophrenia
First Posted Date
2001-04-09
Last Posted Date
2015-06-17
Lead Sponsor
National Institute of Mental Health (NIMH)
Target Recruit Count
1600
Registration Number
NCT00014001
Locations
🇺🇸

Staten Island University Hospital, Staten Island, New York, United States

🇺🇸

Emory University School of Medicine, Atlanta, Georgia, United States

🇺🇸

Northwestern Medical School Department of Psychiatry, Chicago, Illinois, United States

and more 51 locations
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