Lormetazepam

Generic Name: Lormetazepam

Brand Names: -

Drug Type: Small Molecule

Chemical Formula: C_₁₆H_₁₂Cl_₂N_₂O_₂

CAS Number: 848-75-9

Unique Ingredient Identifier: GU56C842ZA

Background: Lormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia . It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.

Indication: For the treatment of short-term insomnia

Associated Conditions: Anxiety Acute, Severe Insomnia, Sleep disorders and disturbances

Associated Therapies: -

Clinical Trials

Pharmacovigilance in Gerontopsychiatric Patients

Phase 3

Terminated

Conditions: Dementia
Depression
Schizophrenia
Psychosomatic Disorders
Anxiety Disorders

Interventions: Drug: Phenobarbital
Drug: Phenytoin
Drug: Carbamazepine
Drug: Oxcarbazepine
Drug: Valproic Acid
Drug: Lamotrigine
Drug: Topiramate
Drug: Gabapentin
Drug: Levetiracetam
Drug: Pregabalin
Drug: Lacosamide
Drug: Clonazepam
Drug: Biperiden
Drug: Levomepromazine
Drug: Fluphenazine
Drug: Perphenazine
Drug: Perazine
Drug: Thioridazine
Drug: Haloperidol
Drug: Melperone
Drug: Pipamperone
Drug: Bromperidol
Drug: Benperidol
Drug: Sertindole
Drug: Ziprasidone
Drug: Flupentixol
Drug: Chlorprothixene
Drug: Zuclopenthixol
Drug: Fluspirilene
Drug: Pimozide
Drug: Clozapine
Drug: Olanzapine
Drug: Quetiapine
Drug: Sulpiride
Drug: Tiapride
Drug: Amisulpride
Drug: Prothipendyl
Drug: Risperidone
Drug: Aripiprazole
Drug: Paliperidone
Drug: Diazepam
Drug: Oxazepam
Drug: Lorazepam
Drug: Bromazepam
Drug: Clobazam
Drug: Alprazolam
Drug: Hydroxyzine
Drug: Buspirone
Drug: Chloral Hydrate
Drug: Flurazepam
Drug: Nitrazepam
Drug: Triazolam
Drug: Lormetazepam
Drug: Temazepam
Drug: Midazolam
Drug: Brotizolam
Drug: Zopiclone
Drug: Zolpidem
Drug: Zaleplon
Drug: Melatonin
Drug: Clomethiazole
Drug: Diphenhydramine
Drug: Promethazine
Drug: Imipramine
Drug: Clomipramine
Drug: Opipramol
Drug: Trimipramine
Drug: Amitriptyline
Drug: Nortriptyline
Drug: Doxepin
Drug: Maprotiline
Drug: Amitriptyline oxide
Drug: Fluoxetine
Drug: Citalopram
Drug: Paroxetine
Drug: Sertraline
Drug: Fluvoxamine
Drug: Escitalopram
Drug: Tranylcypromine
Drug: Moclobemide
Drug: Mianserin
Drug: Trazodone
Drug: Mirtazapine
Drug: Bupropion
Drug: Venlafaxine
Drug: Reboxetine
Drug: Duloxetine
Drug: Agomelatine
Drug: Pyritinol
Drug: Piracetam
Drug: Donepezil
Drug: Rivastigmine
Drug: Galantamine
Drug: Memantine
Drug: Nicergoline
Drug: Acamprosate
Drug: Lithium

First Posted Date: 2015-03-02

Last Posted Date: 2018-02-28

Lead Sponsor: Hannover Medical School

Target Recruit Count: 407

Registration Number: NCT02374567

Locations: 🇩🇪
Bezirkskrankenhaus Augsburg, Augsburg, Germany
🇩🇪
Krankenhaus Hedwigshöhe, Berlin, Germany
🇩🇪
Hannover Medical School, Hannover, Germany

and more 2 locations

Comparison of Lormetazepam and Midazolam Used as Sedatives for Patients That Require Intensive Care

Phase 4

Completed

Conditions: Sedation in Intensive Care Unit Patients

Interventions: Drug: Lormetazepam
Drug: Midazolam

First Posted Date: 2013-12-30

Last Posted Date: 2022-04-13

Lead Sponsor: Claudia Spies

Target Recruit Count: 84

Registration Number: NCT02022592

Locations: 🇩🇪
Department of Anesthesiology and Intensive Care Medicine, Charité - University Medicine, Berlin, Germany
🇩🇪
Clinic for Anesthesiology, Intensive Care Medicine and Painmanagement, Johann-Wolfgang-Goethe-University, Frankfurt, Frankfurt Am Main, Germany
🇩🇪
Clinic for Operative Intensive Care Medicine and Intermediate Care, University of RWTH, Aachen, Germany

Comparison of Volinanserin and Lormetazepam in the Treatment of Insomnia Characterized by Sleep Maintenance Difficulties

Phase 3

Terminated

Conditions: Sleep Initiation and Maintenance Disorders

Interventions: Drug: Volinanserin (M100907)
Drug: Lormetazepam

First Posted Date: 2008-11-11

Last Posted Date: 2009-08-28

Lead Sponsor: Sanofi

Target Recruit Count: 33

Registration Number: NCT00788515

Locations: 🇸🇪
Sanofi-Aventis Administrative Office, Bromma, Sweden

Comparison of Eplivanserin and Lormetazepam in the Treatment of Insomnia Characterized by Sleep Maintenance Difficulties

Phase 3

Completed

Conditions: Sleep Initiation and Maintenance Disorders

Interventions: Drug: eplivanserin (SR46349)
Drug: lormetazepam

First Posted Date: 2008-05-19

Last Posted Date: 2010-11-30

Lead Sponsor: Sanofi

Target Recruit Count: 283

Registration Number: NCT00679900

Locations: 🇪🇸
Sanofi-Aventis Administrative Office, Barcelona, Spain

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