A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403)
适用于急、慢性精神分裂症,对精神分裂症的阴性症状疗效较好,亦可用于治疗偏执状态、亨廷顿病、抽动秽语综合征、躁狂症、神经性厌食、青少年行为障碍等。
Spaulding Clinical Research, West Bend, Wisconsin, United States
Bezirkskrankenhaus Augsburg, Augsburg, Germany
Krankenhaus Hedwigshöhe, Berlin, Germany
Hannover Medical School, Hannover, Germany
Psychiatrische Klinik und Poliklinik fuer Psychiatrie und Psychotherapie der Technischen Universitaet Muenchen am Klinikum rechts der Isar, Munich, Bavaria, Germany
Connecticut Mental Health Center, New Haven, Connecticut, United States
VA Connecticut Healthcare System, West Haven, Connecticut, United States
Pilgrim Psychiatric Center, W. Brentwood, New York, United States
Icahn School of Medicine at Mount Sinai, New York, New York, United States
Manhattan Psychiatric Center, New York, New York, United States
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