Trazodone
- Generic Name
- Trazodone
- Brand Names
- Desyrel, Oleptro
- Drug Type
- Small Molecule
- Chemical Formula
- C19H22ClN5O
- CAS Number
- 19794-93-5
- Unique Ingredient Identifier
- YBK48BXK30
- Background
Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibito...
- Indication
Trazodone is indicated for the treatment of major depressive disorder (MDD). It has been used off-label for adjunct therapy in alcohol dependence, and off-label to treat anxiety and insomnia. It may also be used off-label to treat symptoms of dementia, Alzheimer’s disease, schizophrenia, eating disorders, and fibromyalgia due to its effects on various neurot...
- Associated Conditions
- Alcohol Dependency, Alzheimer's Disease (AD), Anxiety, Dementia, Eating Disorders Symptoms, Fibromyalgia, Insomnia, Major Depressive Disorder (MDD), Pain, Inflammatory, Schizophrenia, Moderate to severe pain
- Associated Therapies
- -
A Double-blind Placebo Controlled Trial of Sentra PM, a Medical Food
- Conditions
- Interventions
- First Posted Date
- 2011-11-09
- Last Posted Date
- 2011-11-09
- Lead Sponsor
- Targeted Medical Pharma
- Target Recruit Count
- 111
- Registration Number
- NCT01468038
- Locations
- 🇺🇸
Targeted Medical Pharma, Los Angeles, California, United States
Comparison of the Pharmacokinetics of Three Generic Medications and Their Respective Brand Preparations
- Conditions
- Interventions
- First Posted Date
- 2011-07-22
- Last Posted Date
- 2011-07-22
- Lead Sponsor
- University of Ottawa
- Target Recruit Count
- 30
- Registration Number
- NCT01400165
- Locations
- 🇨🇦
University of Ottawa, Institute of Mental Health Research, Ottawa, Ontario, Canada
Study of Trazodone & Cognitive Behavioral Therapy to Treat Insomnia
- Conditions
- Interventions
- First Posted Date
- 2011-05-05
- Last Posted Date
- 2020-02-25
- Lead Sponsor
- Milton S. Hershey Medical Center
- Target Recruit Count
- 24
- Registration Number
- NCT01348542
- Locations
- 🇺🇸
Penn State College of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States
Trazodone for Sleep Disorders in Alzheimer's Disease
- Conditions
- Interventions
- First Posted Date
- 2010-06-11
- Last Posted Date
- 2012-10-15
- Lead Sponsor
- Brasilia University Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT01142258
- Locations
- 🇧🇷
Geriatric Medical Centre, Brasilia, Distrito Federal, Brazil
A Study to Compare the Bioavailability of 300 mg Trazodone Hydrochloride Extended-release Caplets and 100 mg Trazodone Hydrochloride Immediate-release Tablets at Steady State
- Conditions
- Interventions
- First Posted Date
- 2010-05-12
- Last Posted Date
- 2012-04-30
- Lead Sponsor
- Labopharm Inc.
- Target Recruit Count
- 30
- Registration Number
- NCT01121926
Comparative Bioavailability Study of Two Prototypes of Trazodone Controlled-release Products and Two Marketed Reference Products in Healthy Volunteers
- First Posted Date
- 2010-05-12
- Last Posted Date
- 2012-04-27
- Lead Sponsor
- Labopharm Inc.
- Target Recruit Count
- 24
- Registration Number
- NCT01121913
A Study to Compare the Bioavailability of 300 mg Trazodone Hydrochloride Extended-release Caplets and 100 mg Trazodone Hydrochloride Immediate-release Tablets (Administered Three Times Daily)
- First Posted Date
- 2010-05-12
- Last Posted Date
- 2012-04-27
- Lead Sponsor
- Labopharm Inc.
- Target Recruit Count
- 26
- Registration Number
- NCT01121900
Trazodone for SSRI-sexual Dsyfunction
- First Posted Date
- 2010-04-02
- Last Posted Date
- 2012-04-24
- Lead Sponsor
- Beitou Armed Forces Hospital, Taipei, Taiwan
- Target Recruit Count
- 56
- Registration Number
- NCT01097980
- Locations
- 🇨🇳
Department of Psychiatry, Beitou Armed Forces Hospital, Taipei, Taiwan
Comparative Bioavailability Study of Extended-release and Immediate-release Trazodone in Healthy Adult Volunteers
- First Posted Date
- 2009-02-09
- Last Posted Date
- 2012-04-27
- Lead Sponsor
- Labopharm Inc.
- Target Recruit Count
- 24
- Registration Number
- NCT00839072
- Locations
- 🇨🇦
Algorithme Pharma Inc., Laval, Quebec, Canada
Treatment of Neuroleptic Induced Acute Akathisia With Trazodone
- First Posted Date
- 2008-04-17
- Last Posted Date
- 2008-06-17
- Lead Sponsor
- BeerYaakov Mental Health Center
- Target Recruit Count
- 13
- Registration Number
- NCT00659919
- Locations
- 🇮🇱
Beer Yaakov MHC, Beer Yaacov, Israel
Drug Development Updates
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