Diazepam

Generic Name
Diazepam
Brand Names
Diastat, Valium, Valtoco 5 Mg Dose Kit
Drug Type
Small Molecule
Chemical Formula
C16H13ClN2O
CAS Number
439-14-5
Unique Ingredient Identifier
Q3JTX2Q7TU
Background

A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an an...

Indication

In general, diazepam is useful in the symptomatic management of mild to moderate degrees of anxiety in conditions dominated by tension, excitation, agitation, fear, or aggressiveness such as may occur in psychoneurosis, anxiety reactions due to stress conditions, and anxiety states with somatic expression.
...

Associated Conditions
Acute Agitation, Alcohol Withdrawal Delirium, Alcohol Withdrawal Hallucinosis, Anxiety, Anxiety Disorders, Apprehension, Refractory Epilepsy, Skeletal Muscle Spasms, Status Epilepticus, Stress (Psychology), Tension, Tremor, Convulsive disorders, Intermittent distinct from a patient’s usual seizure pattern, stereotypic episode Epileptic seizure
Associated Therapies
Sedation, Perioperative management therapy

A Non-inferiority Trial on Pain Relief During Oocyte Retrieval

First Posted Date
2015-07-10
Last Posted Date
2019-03-05
Lead Sponsor
Kwong Wah Hospital
Target Recruit Count
170
Registration Number
NCT02494180

Pharmacovigilance in Gerontopsychiatric Patients

Phase 3
Terminated
Conditions
Interventions
Drug: Phenobarbital
Drug: Phenytoin
Drug: Carbamazepine
Drug: Oxcarbazepine
Drug: Valproic Acid
Drug: Lamotrigine
Drug: Topiramate
Drug: Gabapentin
Drug: Levetiracetam
Drug: Pregabalin
Drug: Lacosamide
Drug: Clonazepam
Drug: Biperiden
Drug: Levomepromazine
Drug: Fluphenazine
Drug: Perphenazine
Drug: Perazine
Drug: Thioridazine
Drug: Haloperidol
Drug: Melperone
Drug: Pipamperone
Drug: Bromperidol
Drug: Benperidol
Drug: Sertindole
Drug: Ziprasidone
Drug: Flupentixol
Drug: Chlorprothixene
Drug: Zuclopenthixol
Drug: Fluspirilene
Drug: Pimozide
Drug: Clozapine
Drug: Olanzapine
Drug: Quetiapine
Drug: Sulpiride
Drug: Tiapride
Drug: Amisulpride
Drug: Prothipendyl
Drug: Risperidone
Drug: Aripiprazole
Drug: Paliperidone
Drug: Diazepam
Drug: Oxazepam
Drug: Lorazepam
Drug: Bromazepam
Drug: Clobazam
Drug: Alprazolam
Drug: Hydroxyzine
Drug: Buspirone
Drug: Chloral Hydrate
Drug: Flurazepam
Drug: Nitrazepam
Drug: Triazolam
Drug: Lormetazepam
Drug: Temazepam
Drug: Midazolam
Drug: Brotizolam
Drug: Zopiclone
Drug: Zolpidem
Drug: Zaleplon
Drug: Melatonin
Drug: Clomethiazole
Drug: Diphenhydramine
Drug: Promethazine
Drug: Imipramine
Drug: Clomipramine
Drug: Opipramol
Drug: Trimipramine
Drug: Amitriptyline
Drug: Nortriptyline
Drug: Doxepin
Drug: Maprotiline
Drug: Amitriptyline oxide
Drug: Fluoxetine
Drug: Citalopram
Drug: Paroxetine
Drug: Sertraline
Drug: Fluvoxamine
Drug: Escitalopram
Drug: Tranylcypromine
Drug: Moclobemide
Drug: Mianserin
Drug: Trazodone
Drug: Mirtazapine
Drug: Bupropion
Drug: Venlafaxine
Drug: Reboxetine
Drug: Duloxetine
Drug: Agomelatine
Drug: Pyritinol
Drug: Piracetam
Drug: Donepezil
Drug: Rivastigmine
Drug: Galantamine
Drug: Memantine
Drug: Nicergoline
Drug: Acamprosate
Drug: Lithium
First Posted Date
2015-03-02
Last Posted Date
2018-02-28
Lead Sponsor
Hannover Medical School
Target Recruit Count
407
Registration Number
NCT02374567
Locations
🇩🇪

Bezirkskrankenhaus Augsburg, Augsburg, Germany

🇩🇪

Krankenhaus Hedwigshöhe, Berlin, Germany

🇩🇪

Hannover Medical School, Hannover, Germany

and more 2 locations

Impact of a One-month Long Detoxification Diazepam Treatment on Early Alcohol Relapse

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2014-09-17
Last Posted Date
2016-09-15
Lead Sponsor
University Hospital, Lille
Target Recruit Count
26
Registration Number
NCT02242955
Locations
🇫🇷

Department of Addiction Medicine, Lille, France

🇫🇷

Outpatient Addiction Center "CSAPA - Le Pari", Lille, France

Therapeutic Effect of Quetiapine on Methamphetamine-Induced Psychosis

First Posted Date
2013-09-11
Last Posted Date
2013-09-11
Lead Sponsor
Chulalongkorn University
Target Recruit Count
80
Registration Number
NCT01939093
Locations
🇹🇭

Thanyarak Institute on Drug Abuse, Pathumthani, Thailand

Vaginal Diazepam for the Treatment of Female Pelvic Pain

First Posted Date
2013-09-10
Last Posted Date
2017-07-26
Lead Sponsor
University of Missouri-Columbia
Target Recruit Count
50
Registration Number
NCT01938092
Locations
🇺🇸

Missouri Center for Female Continence and Advanced Pelvic Surgery, University of Missouri Health System, Columbia, Missouri, United States

Lofexidine for Inpatient Opiate Detox in Singapore

First Posted Date
2012-08-30
Last Posted Date
2015-08-28
Lead Sponsor
Institute of Mental Health, Singapore
Target Recruit Count
112
Registration Number
NCT01675648
Locations
🇸🇬

National Addictions Management Service, Institute of Mental Health, Singapore, Singapore, Singapore

Clinical Quality Improvement of Benzodiazepine-Resistant Alcohol Withdrawal Syndrome

Completed
Conditions
Interventions
First Posted Date
2012-07-30
Last Posted Date
2016-01-13
Lead Sponsor
University of Pittsburgh
Target Recruit Count
792
Registration Number
NCT01652326
Locations
🇺🇸

UPMC, Pittsburgh, Pennsylvania, United States

A Study of The Abuse Liability Potential of RO4917838 in Recreational Drug Users

First Posted Date
2011-09-22
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
177
Registration Number
NCT01438749

A Pharmacokinetic Study of a Single-Dose of Diazepam Nasal Spray in Adult Epileptic Patients Experiencing a Seizure Episode

Phase 2
Completed
Conditions
Interventions
First Posted Date
2011-08-16
Last Posted Date
2017-03-29
Lead Sponsor
Acorda Therapeutics
Target Recruit Count
31
Registration Number
NCT01417078
Locations
🇺🇸

Barrow Neurology Clinics at St Joseph's Hospital, Phoenix, Arizona, United States

🇺🇸

Johns Hopkins University, Baltimore, Maryland, United States

🇺🇸

Vanderbilt University, Nashville, Tennessee, United States

and more 1 locations

A Study of Diazepam After Intranasal and Intravenous Administration to Healthy Volunteers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2011-06-02
Last Posted Date
2019-11-01
Lead Sponsor
University of Minnesota
Target Recruit Count
24
Registration Number
NCT01364558
Locations
🇺🇸

Prism Clinical Research Unit, Saint Paul, Minnesota, United States

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