Temazepam

Generic Name
Temazepam
Brand Names
Restoril
Drug Type
Small Molecule
Chemical Formula
C16H13ClN2O2
CAS Number
846-50-4
Unique Ingredient Identifier
CHB1QD2QSS
Background

Temazepam, like many other similar and related benzodiazepines, acts as a gamma-aminobutyric acid (GABA) modulator and is capable of eliciting a variety of actions including sedation, hypnosis, skeletal muscle relaxation, anticonvulsant activity, and anxiolytic action .
...

Indication

Temazepam is specifically indicated only for the short-term management of insomnia , . Furthermore, such management is generally predominantly associated with the symptomatic relief of transient and short-term insomnia characterized by difficulty in falling asleep, frequent nocturnal awakenings and/or early morning awakenings . In particular, the official pr...

Associated Conditions
Insomnia
Associated Therapies
-

Pharmacovigilance in Gerontopsychiatric Patients

Phase 3
Terminated
Conditions
Interventions
Drug: Phenobarbital
Drug: Phenytoin
Drug: Carbamazepine
Drug: Oxcarbazepine
Drug: Valproic Acid
Drug: Lamotrigine
Drug: Topiramate
Drug: Gabapentin
Drug: Levetiracetam
Drug: Pregabalin
Drug: Lacosamide
Drug: Clonazepam
Drug: Biperiden
Drug: Levomepromazine
Drug: Fluphenazine
Drug: Perphenazine
Drug: Perazine
Drug: Thioridazine
Drug: Haloperidol
Drug: Melperone
Drug: Pipamperone
Drug: Bromperidol
Drug: Benperidol
Drug: Sertindole
Drug: Ziprasidone
Drug: Flupentixol
Drug: Chlorprothixene
Drug: Zuclopenthixol
Drug: Fluspirilene
Drug: Pimozide
Drug: Clozapine
Drug: Olanzapine
Drug: Quetiapine
Drug: Sulpiride
Drug: Tiapride
Drug: Amisulpride
Drug: Prothipendyl
Drug: Risperidone
Drug: Aripiprazole
Drug: Paliperidone
Drug: Diazepam
Drug: Oxazepam
Drug: Lorazepam
Drug: Bromazepam
Drug: Clobazam
Drug: Alprazolam
Drug: Hydroxyzine
Drug: Buspirone
Drug: Chloral Hydrate
Drug: Flurazepam
Drug: Nitrazepam
Drug: Triazolam
Drug: Lormetazepam
Drug: Temazepam
Drug: Midazolam
Drug: Brotizolam
Drug: Zopiclone
Drug: Zolpidem
Drug: Zaleplon
Drug: Melatonin
Drug: Clomethiazole
Drug: Diphenhydramine
Drug: Promethazine
Drug: Imipramine
Drug: Clomipramine
Drug: Opipramol
Drug: Trimipramine
Drug: Amitriptyline
Drug: Nortriptyline
Drug: Doxepin
Drug: Maprotiline
Drug: Amitriptyline oxide
Drug: Fluoxetine
Drug: Citalopram
Drug: Paroxetine
Drug: Sertraline
Drug: Fluvoxamine
Drug: Escitalopram
Drug: Tranylcypromine
Drug: Moclobemide
Drug: Mianserin
Drug: Trazodone
Drug: Mirtazapine
Drug: Bupropion
Drug: Venlafaxine
Drug: Reboxetine
Drug: Duloxetine
Drug: Agomelatine
Drug: Pyritinol
Drug: Piracetam
Drug: Donepezil
Drug: Rivastigmine
Drug: Galantamine
Drug: Memantine
Drug: Nicergoline
Drug: Acamprosate
Drug: Lithium
First Posted Date
2015-03-02
Last Posted Date
2018-02-28
Lead Sponsor
Hannover Medical School
Target Recruit Count
407
Registration Number
NCT02374567
Locations
🇩🇪

Bezirkskrankenhaus Augsburg, Augsburg, Germany

🇩🇪

Krankenhaus Hedwigshöhe, Berlin, Germany

🇩🇪

Hannover Medical School, Hannover, Germany

and more 2 locations

Efficacy and Safety of Temazepam in HIV Seropositive Patients With Insomnia

Phase 4
Completed
Conditions
Interventions
First Posted Date
2014-06-03
Last Posted Date
2015-03-10
Lead Sponsor
Duke University
Target Recruit Count
44
Registration Number
NCT02153788

Comparison of Temazepam and Acetazolamide to Treat Difficulty Sleeping at High Altitude

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2012-01-27
Last Posted Date
2015-04-23
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
34
Registration Number
NCT01519544
Locations
🇳🇵

Himalayan Rescue Location clinic in Manang, Manang, District of Manang, Nepal

Study to Investigate the Effects of Melatonin, Temazepam & Zolpidem on Sleep EEG in Men and Women

First Posted Date
2009-07-16
Last Posted Date
2011-08-08
Lead Sponsor
University of Surrey
Target Recruit Count
16
Registration Number
NCT00940550
Locations
🇬🇧

Surrey CRC, University of Surrey, Egerton Road, Guildford, Surrey, United Kingdom

The Treatment of Insomnia in Patients With HIV Disease

First Posted Date
2007-04-27
Last Posted Date
2013-07-30
Lead Sponsor
Duke University
Target Recruit Count
44
Registration Number
NCT00465972
Locations
🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

Effects of Temazepam in Patients With Chronic Pulmonary Obstructive Disease

Phase 3
Completed
Conditions
First Posted Date
2005-10-28
Last Posted Date
2007-11-02
Lead Sponsor
Rijnstate Hospital
Target Recruit Count
14
Registration Number
NCT00245661
Locations
🇳🇱

Rijnstate Hospital, Arnhem, Gelderland, Netherlands

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